ArticleThe Plant cell2005
Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola.
Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
150 citing papers in PubMed, 352 citations in OpenAlex.
- Secreted molecules as modulators of somatic embryogenesis efficiency - an overview.Frontiers in plant science · 2026Review
- Beyond the surface: the plant secretome as a bridge between the cell and its environment.Planta · 2025Review
- A GDSL motif-containing lipase modulates Sclerotinia sclerotiorum resistance in Brassica napus.Plant physiology · 2024Article
- OsGELP77, a QTL for broad-spectrum disease resistance and yield in rice, encodes a GDSL-type lipase.Plant biotechnology journal · 2024Article
- Characterization of two SGNH family cell death-inducing proteins from the horticulturally important fungal pathogen Botrytis cinerea based on the optimized prokaryotic expression system.Molecular horticulture · 2024Article
- The chromosome-scale genome and the genetic resistance machinery against insect herbivores of the Mexican toloache, Datura stramonium.G3 (Bethesda, Md.) · 2024Article
- Genetic Analysis of Partially Resistant and Susceptible Chickpea Cultivars in Response toInternational journal of molecular sciences · 2024Article
- Identification, evolution, and expression of GDSL-type Esterase/Lipase (GELP) gene family in three cotton species: a bioinformatic analysis.BMC genomics · 2023Article
- Metabolic and Molecular Rearrangements of Sauvignon Blanc (Plants (Basel, Switzerland) · 2023Article
- Cosuppression of AtGELP22 and AtGELP23, two ubiquitinated target proteins of RING E3 ligase AtAIRP5, increases tolerance to drought stress in Arabidopsis.Plant molecular biology · 2023Article
- TMT-Based Proteomic Analysis ofFoods (Basel, Switzerland) · 2023Article
- GDSL Esterase/Lipase GELP1 Involved in the Defense of Apple Leaves againstInternational journal of molecular sciences · 2023Article
- LSPpred Suite: Tools for Leaderless Secretory Protein Prediction in Plants.Plants (Basel, Switzerland) · 2023Article
- Article
- The roles of plant proteases and protease inhibitors in drought response: a review.Frontiers in plant science · 2023Review
- The EXO70 inhibitor Endosidin2 alters plasma membrane protein composition in Arabidopsis roots.Frontiers in plant science · 2023Article
- Comparative transcriptome profiling reveals differential defense responses amongFrontiers in plant science · 2023Article
- NGS transcriptomic analysis uncovers the possible resistance mechanisms of olive toFrontiers in plant science · 2023Article
- A spatiotemporal atlas of organogenesis in the development of orchid flowers.Nucleic acids research · 2022Article
- SWOLLEN TAPETUM AND STERILITY 1 is required for tapetum degeneration and pollen wall formation in rice.Plant physiology · 2022Article
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis thaliana secretome was analyzed by the proteomic approach, which led to the identification of secreted proteins implicated in many aspects of cell biology. We then investigated the change in the Arabidopsis secretome in response to salicylic acid and identified several proteins involved in pathogen response. One of these, a secreted lipase with a GDSL-like motif designated GDSL LIPASE1 (GLIP1), was further characterized for its function in disease resistance. glip1 plants were markedly more susceptible to infection by the necrotrophic fungus Alternaria brassicicola compared with the parental wild-type plants. The recombinant GLIP1 protein possessed lipase and antimicrobial activities that directly disrupt fungal spore integrity. Furthermore, GLIP1 appeared to trigger systemic resistance signaling in plants when challenged with A. brassicicola, because pretreatment of the glip1 mutant with recombinant GLIP1 protein inhibited A. brassicicola-induced cell death in both peripheral and distal leaves. Moreover, glip1 showed altered expression of defense- and ethylene-related genes. GLIP1 transcription was increased by ethephon, the ethylene releaser, but not by salicylic acid or jasmonic acid. These results suggest that GLIP1, in association with ethylene signaling, may be a critical component in plant resistance to A. brassicicola.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.