ReviewEnvironmental health : a global access science source2005
Teratogenicity of depleted uranium aerosols: a review from an epidemiological perspective.
Review in Environmental health : a global access science source, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Weaponised uranium and adverse health outcomes in Iraq: a systematic review.BMJ global health · 2021Pooled it
- The GALENOS approach to triangulating evidence: a structured approach for integrating information from human and animal studies.BMC medical research methodology · 2026Article
- US drinking water quality: exposure risk profiles for seven legacy and emerging contaminants.Journal of exposure science & environmental epidemiology · 2024Review
- Article
- Folic Acid Fortification Prevents Morphological and Behavioral Consequences of X-Ray Exposure During Neurulation.Frontiers in behavioral neuroscience · 2020Article
- Human exposure to uranium in South African gold mining areas using barber-based hair sampling.PloS one · 2019Article
- A Review on Toxicodynamics of Depleted Uranium.Iranian journal of pharmaceutical research : IJPR · 2019Review
- Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis.Oncotarget · 2018Article
- Article
- Health Effects and Environmental Justice Concerns of Exposure to Uranium in Drinking Water.Current environmental health reports · 2016Review
- Improvements in Neonatal and Childhood Medical Care - Perspective from the Balkans.Frontiers in public health · 2015Article
- Birth defects in Iraq and the plausibility of environmental exposure: A review.Conflict and health · 2012Article
- Uranium and other contaminants in hair from the parents of children with congenital anomalies in Fallujah, Iraq.Conflict and health · 2011Article
- Four polygamous families with congenital birth defects from Fallujah, Iraq.International journal of environmental research and public health · 2011Article
- The toxicity of depleted uranium.International journal of environmental research and public health · 2010Review
- Drinking water with uranium below the U.S. EPA water standard causes estrogen receptor-dependent responses in female mice.Environmental health perspectives · 2007Article
- Reproductive health of Gulf War veterans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepleted uranium is being used increasingly often as a component of munitions in military conflicts. Military personnel, civilians and the DU munitions producers are being exposed to the DU aerosols that are generated.
methodsWe reviewed toxicological data on both natural and depleted uranium. We included peer reviewed studies and gray literature on birth malformations due to natural and depleted uranium. Our approach was to assess the "weight of evidence" with respect to teratogenicity of depleted uranium.
resultsAnimal studies firmly support the possibility that DU is a teratogen. While the detailed pathways by which environmental DU can be internalized and reach reproductive cells are not yet fully elucidated, again, the evidence supports plausibility. To date, human epidemiological data include case examples, disease registry records, a case-control study and prospective longitudinal studies. DISCUSSION: The two most significant challenges to establishing a causal pathway between (human) parental DU exposure and the birth of offspring with defects are: i) distinguishing the role of DU from that of exposure to other potential teratogens; ii) documentation on the individual level of extent of parental DU exposure. Studies that use biomarkers, none yet reported, can help address the latter challenge. Thoughtful triangulation of the results of multiple studies (epidemiological and other) of DU teratogenicity contributes to disentangling the roles of various potentially teratogenic parental exposures. This paper is just such an endeavor.
conclusionIn aggregate the human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to DU.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.