Trial reportThe Journal of physiology2005
Movement-related frequency modulation of beta oscillatory activity in the human subthalamic nucleus.
Trial report in The Journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 177 citations in OpenAlex.
- Mapping of subthalamic nucleus using microelectrode recordings during deep brain stimulation.Scientific reports · 2020Trial
- Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients.Journal of neurology, neurosurgery, and psychiatry · 2011Trial
- Dopamine-dependent non-linear correlation between subthalamic rhythms in Parkinson's disease.The Journal of physiology · 2006Trial
- The CM-aGPi Network in the Generation of Tics in Tourette Syndrome.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Subthalamic nucleus input-output dynamics are correlated with Parkinson's burden and treatment efficacy.NPJ Parkinson's disease · 2024Article
- Gait-related beta-gamma phase amplitude coupling in the subthalamic nucleus of parkinsonian patients.Scientific reports · 2024Article
- Cerebellar activity in PINK1 knockout rats during volitional gait.Brain communications · 2024Article
- Cerebellar activity in hemi-parkinsonian rats during volitional gait and freezing.Brain communications · 2024Article
- Asymmetries of the subthalamic activity in Parkinson's disease: phase-amplitude coupling among local field potentials.Brain communications · 2024Article
- Tuned to Tremor: Increased Sensitivity of Cortico-Basal Ganglia Neurons to Tremor Frequency in the MPTP Nonhuman Primate Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Corticostriatal beta oscillation changes associated with cognitive function in Parkinson's disease.Brain : a journal of neurology · 2023Article
- Hyper-parameter tuning and feature extraction for asynchronous action detection from sub-thalamic nucleus local field potentials.Frontiers in human neuroscience · 2023Article
- Amplitude and frequency modulation of subthalamic beta oscillations jointly encode the dopaminergic state in Parkinson's disease.NPJ Parkinson's disease · 2022Article
- Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings.NPJ Parkinson's disease · 2022Article
- Article
- A Systematic Review of Neurofeedback for the Management of Motor Symptoms in Parkinson's Disease.Brain sciences · 2021Review
- Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts.NPJ Parkinson's disease · 2021Article
- Abnormal Cortico-Basal Ganglia Neurotransmission in a Mouse Model of l-DOPA-Induced Dyskinesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Movement-related EEG signatures associated with freezing of gait in Parkinson's disease: an integrative analysis.Brain communications · 2021Article
- Rhythm and Music-Based Interventions in Motor Rehabilitation: Current Evidence and Future Perspectives.Frontiers in human neuroscience · 2021Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Event-related changes of brain electrical rhythms are typically analysed as amplitude modulations of local field potential (LFP) oscillations, like radio amplitude modulation broadcasting. In telecommunications, frequency modulation (FM) is less susceptible to interference than amplitude modulation (AM) and is therefore preferred for high-fidelity transmissions. Here we hypothesized that LFP rhythms detected from deep brain stimulation (DBS) electrodes implanted in the subthalamic nucleus (STN) in patients with Parkinson's disease could represent movement-related activity not only in AM but also in FM. By combining adaptive autoregressive identification with spectral power decomposition, we were able to show that FM of low-beta (13-20 Hz) and high-beta (20-35 Hz) rhythms significantly contributes to the involvement of the human STN in movement preparation, execution and recovery, and that the FM patterns are regulated by the dopamine levels in the system. Movement-related FM of beta oscillatory activity in the human subthalamic nucleus therefore provides a novel informational domain for rhythm-based pathophysiological models of cortico-basal ganglia processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.