ArticleEuropean journal of epidemiology2005
Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men.
Article in European journal of epidemiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 57 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Patient Education Manual on Pain, Range of Motion and Function in Patient With Knee Osteoarthritis
Effects of Low Level Laser Therapy on Knee Pain and Function in Patients With Knee Osteoarthritis
Who cites it
57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Association of smoking with knee osteoarthritis structural defects and symptoms: an individual participant data meta-analysis.Scientific reports · 2024Pooled it
- Impact of smoking on the incidence and post-operative complications of total knee arthroplasty: A systematic review and meta-analysis of cohort studies.Bosnian journal of basic medical sciences · 2022Pooled it
- Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies.BMJ open · 2015Pooled it
- The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis.BMC public health · 2009Pooled it
- Systematic review of the prevalence of radiographic primary hip osteoarthritis.Clinical orthopaedics and related research · 2009Pooled it
- Prevalence of osteoarthritis in individuals with COPD: a systematic review.International journal of chronic obstructive pulmonary diseasePooled it
- Weight trajectories and obesity onset between 17 and 60 years of age, and cause-specific mortality: the Obesity and Disease Development Sweden (ODDS) pooled cohort study.EClinicalMedicine · 2026Article
- Unraveling the connection between obesity, metabolic syndrome and osteoarthritis risk: a large-observational study.Diabetology & metabolic syndrome · 2025Article
- Prevalence of Knee Osteoarthritis in India: A Systematic Review and Meta-Analysis of Population-Based Studies.Indian journal of orthopaedics · 2025Review
- Smoking can increase the risk of osteoarthritis in European women.Scientific reports · 2025Article
- Association of height, BMI, and smoking status with prostate cancer risk before and after the introduction of PSA testing in Sweden.Scientific reports · 2025Article
- Physical health in young males and risk of chronic musculoskeletal, cardiovascular, and respiratory diseases by middle age: A population-based cohort study.PLoS medicine · 2025Article
- Assessing the impact of tobacco smoke exposure on earlyonset osteoarthritis: A cross-sectional analysis of secondary data from the National Health and Nutrition Examination Survey (NHANES), 1999-2020.Tobacco induced diseases · 2025Article
- Unveiling the future: Bibliometric analysis on the application of nanomaterials in osteoarthritis (2006-2023).Heliyon · 2024Review
- Low-, moderate-, and high-risk obesity in association with cost drivers, costs over the lifecycle, and life expectancy.BMC public health · 2024Article
- Cohort profile: The Obesity and Disease Development Sweden (ODDS) study, a pooled cohort.BMJ open · 2024Article
- Investigation of the Associations of Smoking With Hip Osteoarthritis: A Baseline Cross-Sectional and Four- to Five-Year Longitudinal Multicohort Study.ACR open rheumatology · 2024Article
- Association of smoking and osteoarthritis in US (NHANES 1999-2018).Scientific reports · 2023Article
- Obesity is associated with an increased risk of undergoing knee replacement in Australia.ANZ journal of surgery · 2022Article
- Smoking Cessation Rates among Patients with Rheumatoid Arthritis and Osteoarthritis Following the 'Gold Standard Programme' (GSP): A Prospective Analysis from the Danish Smoking Cessation Database.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to estimate the risk of severe osteoarthritis, with the need for arthroplasty, in the knee and/or hip according to body mass index (BMI) both within a normal range and in persons with high BMI. Furthermore, we wanted to study the significance of smoking.
methodsThis study identifies male construction workers participating in a national health control program (n = 320,192). The incidence rate for joint replacement was found by matching with the Swedish hospital discharge register between 1987 and 1998. BMI and smoking habit was registered at the time of the health examination.
resultsIn total 1495 cases of osteoarthritis of the hip and 502 cases of osteoarthritis of the knee were identified and included in this analysis. The incidence rate was found to increase linearly to the BMI even within low and 'normal' BMI. The relative risk for osteoarthritis of the hip was more than two times higher in persons with a BMI of 20-24 than in men with a BMI 17-19. There was almost a doubling of the risk of severe knee osteoarthritis with an increase in BMI of 5 kg/m2. Smoker had a lower risk of osteoarthritis than non-smokers and ex-smokers.
conclusionsBMI is an important predictor of osteoarthritis even within normal BMI. A decreased risk of osteoarthritis of the hip was found in smokers, but the effect was weak compared to that of BMI or age. Contrary to studies of radiographic osteoarthritis our study indicates higher risk of hip than of knee osteoarthritis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.