Evidence map›Paper›PMID 16120972›Full record

ReviewImmunologic research2005

Immune regulation during allergic bronchopulmonary mycosis: lessons taught by two fungi.

Shikha Arora, Gary B Huffnagle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Infections caused by Scedosporium spp.Clinical microbiology reviews · 2008
    Review
  9. Article
  10. Article
  11. Allergic bronchopulmonary aspergillosis.The journal of allergy and clinical immunology. In practice
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shikha AroraImmunology Graduate Program, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Gary B Huffnagle
University of Michigan–Ann Arbor · US

Funding

MODULATION OF TH1/TH2 RESPONSES BY INNATE IMMUNITYR01HL065912 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUFFNAGLE, GARY B. · 2000 to 2004
$1.5M
NHLBI NIH HHS R01-HL65912
6 · The paper itself

Abstract

Allergic bronchopulmonary mycosis (ABPM) is a devastating pulmonary disease that results from an aggressive allergic response to fungal colonization in the airways. Animal models using either fungal antigen or live infection reproduce most of the clinical features seen during ABPM in humans. Results from these studies have facilitated a detailed analysis of the key factors involved in the afferent as well as efferent phase of the disease. This review focuses on allergic bronchopulmonary disease caused by two different fungi (Aspergillus fumigatus and Cryptococcus neoformans): allergic bronchopulmonary aspergillosis and allergic bronchopulmonary cryptococcosis. Observations from both models underline the importance of initial innate immune responses and their translation into appropriate adaptive responses. In addition, data derived from knockout studies give emphasis to targeting cytokines and chemokines as a therapeutic strategy in the treatment of ABPM.

Indexed as

AnimalsAspergillosis, Allergic BronchopulmonaryCryptococcosisHumansT-Lymphocytes, Regulatory

Identifiers

PMID16120972
OpenAlexW2314313322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.