Trial reportBritish journal of clinical pharmacology2005
Concomitant use of analgesics and psychotropics in home-dwelling elderly people-Kuopio 75 + study.
Trial report in British journal of clinical pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Canadian guideline for safe and effective use of opioids for chronic noncancer pain: clinical summary for family physicians. Part 2: special populations.Canadian family physician Medecin de famille canadien · 2011Guideline
- Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol.Age (Dordrecht, Netherlands) · 2012Trial
- Drug prescription before and after dialysis initiation in older patients: a nationwide study.BMC geriatrics · 2026Article
- Article
- Association between psychotropic drug use and handgrip strength in older hospitalized patients.European geriatric medicine · 2021Article
- Prevalence and persistent use of analgesic drugs in older adults receiving domiciliary care at baseline-A longitudinal study.Health science reports · 2021Article
- Chronic Pain in the Elderly with Cognitive Decline: A Narrative Review.Pain and therapy · 2019Review
- Prevalence and persistent use of psychotropic drugs in older adults receiving domiciliary care at baseline.BMC geriatrics · 2019Article
- Psychotropic Polypharmacy in Adults 55 Years or Older: A Risk for Impaired Global Cognition, Executive Function, and Mobility.Frontiers in pharmacology · 2019Article
- Categorization and association analysis of risk factors for adverse drug events.European journal of clinical pharmacology · 2018Review
- The type and prevalence of the use of analgesics among inpatients in a geriatric psychiatry department.Therapeutic advances in psychopharmacology · 2016Article
- [Opioids for noncancer pain in the elderly].Schmerz (Berlin, Germany) · 2015Article
- Review on microbiota and effectiveness of probiotics use in older.World journal of clinical cases · 2015Review
- Association between use of multiple psychoactive medicines and hospitalization for falls: retrospective analysis of a large healthcare claim database.Drug safety · 2014Article
- Prevalence of potential drug-drug interactions in cancer patients treated with oral anticancer drugs.British journal of cancer · 2013Article
- Potentially inappropriate drug use among older persons in Finland: application of a new national categorization.European journal of clinical pharmacology · 2013Article
- CNS medications as predictors of precipitous cognitive decline in the cognitively disabled aged: a longitudinal population-based study.Dementia and geriatric cognitive disorders extra · 2012Article
- Combination drug therapy for chronic pain: a call for more clinical studies.The journal of pain · 2011Review
- Concomitant use of SSRIs, NSAIDs/aspirin and gastroprotective drugs among residents of long-term care facilities: a medical record review.Clinical drug investigation · 2011Article
- Potential drug interactions and duplicate prescriptions among ambulatory cancer patients: a prevalence study using an advanced screening method.BMC cancer · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate the extent of concomitant use of analgesic and psychotropic medicines among home-dwelling elderly people aged at least 75 years in Finland.
methodsThis was a population-based study in Finland, performed as part of Kuopio 75 + study focusing on the clinical epidemiology of diseases, medication and functional capacity. A random sample of 700 persons was drawn from the total population of the city of Kuopio, eastern Finland, aged 75 years on January 1, 1998 (n = 4518). Ninety-nine persons could not be examined and 78 were living in long-term institutions, so that the number of home-dwelling elderly persons amounted to 523. A trained nurse interviewed the participants about their use of medicines, and a geriatrician examined their overall physical and mental status. Dementia and depression were diagnosed according to the DSM IV criteria. Both regular and irregular prescribed and nonprescribed drug use was recorded.
resultsEvery fourth elderly person (27.2%) used analgesics and psychotropics concomitantly, this use becoming twice as common with advancing age (19.6% in the age group 75-79 years, 38.2% among the oldest, aged 85 + years). Concomitant use of psychotropics and opioids also became more common with increasing age (2.8% in age group 75-79 years and 9.6% in the oldest group, aged 85 + years). The use of opioids was nearly twice as common among concomitant users (19.7%) than among those using only analgesics (11.3%). Concomitant users suffered from interfering daily pain and daily pain at rest more commonly than nonusers of analgesics. Depression, sleeping problems and polypharmacy were more common among the concomitant users, who had also had more hip fractures than the rest.
conclusionsConcomitant use of analgesics and psychotropics becomes more common with advancing age and is a potential risk factor for adverse drug effects.
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