Evidence map›Paper›PMID 16119432›Full record

ArticleEuropean journal of epidemiology2005

Genotype frequencies at codon 129 of the prion protein gene in Brazil: Implications in susceptibility to variant Creutzfeldt-Jakob disease compared to European and Asian populations.

Erich Vinicius de Paula, Marcelo Addas-Carvalho, Devanira Souza Paixao Costa, Sara Terezinha Olalla Saad, Simone Cristina Olenscki Gilli

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of epidemiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erich Vinicius de PaulaHaematology and Haemotherapy Centre, State University of Campinas, Rua Carlos Chagas 480, CEP 13083-970 Campinas, SP, Brazil.
Marcelo Addas-Carvalho
Devanira Souza Paixao Costa
Sara Terezinha Olalla Saad
Simone Cristina Olenscki Gilli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A polymorphism at codon 129 of the prion protein gene has been shown to confer genetic susceptibility to prion diseases, and to influence the epidemic course of variant Creutzfeldt-Jakob disease. We employed a PCR-endonuclease digestion-based assay to investigate this genetic trait in Brazil, and then compared our results to previously published data from several European and Asian countries.

Indexed as

GenotypePolymorphism, GeneticAdolescentAdultAgedAsian PeopleBlack PeopleBrazilCodonCreutzfeldt-Jakob SyndromeGene FrequencyGenetic Predisposition to DiseaseHumansIndians, South AmericanMiddle AgedPeptide FragmentsCodonPeptide Fragmentsprion protein (127-147)Prions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.