ArticleImmunity & ageing : I & A2005
Life and death of lymphocytes: a role in immunesenescence.
Article in Immunity & ageing : I & A, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- High Frequencies of Senescent and Exhausted Natural Killer Cells and SARS-CoV-2-Specific Memory CD8Viruses · 2026Article
- The Role and Research Progress of CD8Biomedicines · 2025Review
- White Blood Cells in Neurodegenerative Diseases in the Context of Neuroinflammation.Molecular neurobiology · 2025Review
- Neuroinflammation in Alzheimer's disease: insights from peripheral immune cells.Immunity & ageing : I & A · 2024Review
- Article
- Angiotensin Converting Enzyme 1 Expression in the Leukocytes of Adults Aged 64 to 67 Years.JMIRx med · 2023Article
- Comparison of the deep immune profiling of B cell subsets between healthy adults and Sjögren's syndrome.Annals of medicine · 2022Article
- Article
- The Presence of a Marked Imbalance Between Regulatory T Cells and Effector T Cells Reveals That Tolerance Mechanisms Could Be Compromised in Heart Transplant Children.Transplantation direct · 2021Article
- [Targeting BCMA in multiple myeloma using chimeric antigen receptor-engineered T cells].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2019Article
- Clinical and hematological data to group different chronic kidney disease patients: A practical approach to establish different groups of patients.Journal of clinical laboratory analysis · 2018Article
- Targeting FLT3 in acute myeloid leukemia using ligand-based chimeric antigen receptor-engineered T cells.Journal of hematology & oncology · 2018Article
- Proapoptotic CD95L levels in normal human serum and sera of breast cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- Immune profiling and cancer post transplantation.World journal of nephrology · 2015Review
- Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury.EXCLI journal · 2014Review
- Ageing combines CD4 T cell lymphopenia in secondary lymphoid organs and T cell accumulation in gut associated lymphoid tissue.Immunity & ageing : I & A · 2014Article
- A novel B cell population revealed by a CD38/CD24 gating strategy: CD38(-)CD24 (-) B cells in centenarian offspring and elderly people.Age (Dordrecht, Netherlands) · 2013Article
- Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines.BMC cancer · 2013Article
- The importance of the nurse cells and regulatory cells in the control of T lymphocyte responses.BioMed research international · 2013Review
- Kidney transplantation and the ageing immune system.Nature reviews. Nephrology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Human aging is associated with progressive decline in immune functions, increased frequency of infections. Among immune functions, a decline in T cell functions during aging predominates. In this review, we will discuss the molecular signaling in two major pathways of apoptosis, namely death receptor pathway and mitochondrial pathway, and their alterations in both T and B lymphocytes in human aging with a special emphasis on naïve and different memory subsets of CD8+ T cells. We will also discuss a possible role of lymphocyte apoptosis in immune senescence.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.