Evidence map›Paper›PMID 16113348›Full record

ArticleInfection and immunity2005

Viability of a capsule- and lipopolysaccharide-deficient mutant of Neisseria meningitidis.

Martine P Bos, Jan Tommassen

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. LPS in gram-negative bacterial growth and physiology: outside but fully integrated.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  3. Article
  4. Article
  5. Phospholipid retention in the absence of asymmetry strengthens the outer membrane permeability barrier to last-resort antibiotics.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  6. Article
  7. Lipid A Has Significance for Optimal Growth ofFrontiers in cellular and infection microbiology · 2018
    Article
  8. Article
  9. Review
  10. Bacterial fatty acid metabolism in modern antibiotic discovery.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2017
    Review
  11. Review
  12. Article
  13. Expression of the Gene for Autotransporter AutB ofFrontiers in cellular and infection microbiology · 2016
    Article
  14. Article
  15. Lipopolysaccharide transport to the cell surface: biosynthesis and extraction from the inner membrane.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Martine P BosDepartment of Molecular Microbiology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands. M.P.Bos@bio.uu.nl
Jan Tommassen
Utrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neisseria meningitidis is the only lipopolysaccharide (LPS)-producing gram-negative bacterial species shown to be viable also without LPS. It was thought that the presence of capsular polysaccharide is necessary for this unusual feature. However, we show now that no part of the capsule gene cluster is required for maintaining LPS deficiency in N. meningitidis.

Indexed as

Gene DeletionLipopolysaccharidesAcyltransferasesBacterial CapsulesGenetic MarkersMultigene FamilyNeisseria meningitidisacyl-(acyl-carrier-protein)-UDP-N-acetylglucosamine acyltransferaseAcyltransferasesGenetic MarkersLipopolysaccharides

Identifiers

PMID16113348
PMCPMC1231088
OpenAlexW2142551389

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.