Evidence map›Paper›PMID 16113341›Full record

ArticleInfection and immunity2005

Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing fever.

Alan G Barbour, Adrienne D Putteet-Driver, Jonas Bunikis

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Isolation and molecular characterization of a novel relapsing fever groupCurrent research in parasitology & vector-borne diseases · 2024
    Article
  2. Pathogenesis of Relapsing Fever.Current issues in molecular biology · 2021
    Review
  3. First detection and molecular identification of Borrelia species in Bactrian camel (Camelus bactrianus) from Northwest China.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018
    Article
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  7. Phylogeny of a relapsing fever Borrelia species transmitted by the hard tick Ixodes scapularis.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alan G BarbourPacific-Southwest Center, 346 Hewitt Hall, University of California Irvine, Irvine, CA 92697-4025, USA. abarbour@uci.edu
Adrienne D Putteet-Driver
Jonas Bunikis
University of California, Irvine · US

Funding

MOLECULAR BASIS OF BORRELIA PATHOGENESISR37AI024424 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARBOUR, ALAN G. · 2001 to 2010
$3.5M
MOLECULAR BASIS OF BORRELIA PATHOGENESISR01AI024424 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BARBOUR, ALAN G. · 1987 to 2000
$339k
NIAID NIH HHS AI24424NIAID NIH HHS R01 AI024424NIAID NIH HHS R37 AI024424
6 · The paper itself

Abstract

Unlike Borrelia burgdorferi, the relapsing fever agent Borrelia hermsii and the related Borrelia miyamotoi had purA and purB genes of the purine salvage pathway. These were located among the rRNA genes. Phylogenetic analysis indicated that these genes had a different evolutionary history than those of orthologs in other spirochetes.

Indexed as

Gene Transfer, HorizontalAdenylosuccinate LyaseAdenylosuccinate SynthaseAnimalsBorreliaDNA, IntergenicHypoxanthine PhosphoribosyltransferaseMolecular Sequence DataPhylogenyPurinesRelapsing FeverAdenylosuccinate LyaseAdenylosuccinate SynthaseDNA, IntergenicHypoxanthine PhosphoribosyltransferasePurines

Identifiers

PMID16113341
PMCPMC1231056
OpenAlexW2171248194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.