Evidence map›Paper›PMID 16112120›Full record

Trial reportAtherosclerosis2006

Association between nutrient intake and peripheral artery disease: results from the InCHIANTI study.

Raffaele Antonelli-Incalzi, Claudio Pedone, Mary M McDermott, Stefania Bandinelli, Benedetta Miniati, Raffaele Molino Lova, Fulvio Lauretani, Luigi Ferrucci

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Atherosclerosis, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Raffaele Antonelli-IncalziCattedra di Geriatria, Università Campus Biomedico, Rome, Italy.
Claudio Pedone
Mary M McDermott
Stefania Bandinelli
Benedetta Miniati
Raffaele Molino Lova
Fulvio Lauretani
Luigi Ferrucci
Don Carlo Gnocchi Foundation · ITIstituto Nazionale di Riposo e Cura per Anziani · ITUniversità Campus Bio-Medico · ITNational Institutes of Health · USNorthwestern University · US

Funding

Intramural NIH HHS Z99 AG999999
6 · The paper itself

Abstract

backgroundLittle is known about the relationship between dietary patterns and peripheral arterial disease (PAD). Our aim was to estimate the association between nutrient intake and diagnosis of PAD. METHODS AND

resultsWe assessed the nutrient intake of 1251 home-dwelling subjects enrolled in the InCHIANTI study, mean age 68 years (S.D.: 15). We explored the relationship between nutrient intake, obtained through the European Prospective Investigation into Cancer and Nutrition (EPIC) questionnaire, and PAD, defined as an ankle-brachial index (ABI)<0.90. After adjustment for potential confounders, we found a reduction of the risk of having an ABI<0.90 associated with vegetable lipid intake>or=34.4 g/day (OR: 0.39; 95% CI: 0.16-0.97), Vitamin E intake>or=7.726 mg/day (OR: 0.37; 95% CI 0.16-0.84) and higher serum HDL cholesterol concentration (OR: 0.76; 95% CI: 0.63-0.92 for 10mg/dl increase). Age (OR: 1.11; 95% CI 1.07-1.14 for 1 year increase), smoking (OR: 1.03; 95% CI: 1.01-1.04 for 10 packs/year increase) and pulse pressure (OR: 1.11; 95% CI: 1.03-1.19 for 5 mmHg increase) were associated with an increased risk of PAD.

conclusionsA higher intake of vegetable lipids, Vitamin E and higher concentrations of serum HDL cholesterol characterize subjects free from PAD. Prospective studies are needed to verify whether this dietary pattern and/or interventions aimed at increasing HDL cholesterol exert some protective effect against PAD.

Indexed as

Dietary SupplementsAgedAgingArteriosclerosisBlood PressureCholesterol, HDLFemaleFollow-Up StudiesHumansIncidenceItalyMaleNutritional Physiological PhenomenaPrognosisProspective StudiesRisk FactorsCholesterol, HDL

Identifiers

PMID16112120
PMCPMC2645647
OpenAlexW2072603756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.