Evidence map›Paper›PMID 16109818›Full record

ArticleOccupational and environmental medicine2005

Mould/dampness exposure at home is associated with respiratory disorders in Italian children and adolescents: the SIDRIA-2 Study.

M Simoni, E Lombardi, G Berti, F Rusconi, S La Grutta, S Piffer, M G Petronio, C Galassi, F Forastiere, G Viegi and 1 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Occupational and environmental medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 109 citations in OpenAlex.

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  10. The burden of rhinitis and rhinoconjunctivitis in adolescents.Allergy, asthma & immunology research · 2015
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  11. Article
  12. Prevalence of dampness and mold in European housing stock.Journal of exposure science & environmental epidemiology · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

M SimoniPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy.
E Lombardi
G Berti
F Rusconi
S La Grutta
S Piffer
M G Petronio
C Galassi
F Forastiere
G Viegi
SIDRIA-2 Collaborative Group
Istituto di Fisiologia Clinica · ITMeyer Children's Hospital · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · ITAzienda Ospedaliero Universitaria San Giovanni Battista · ITAzienda Sanitaria Locale Roma 3 · ITAzienda Unità Sanitaria Locale 11 di Empoli · ITBitron (Italy) · ITProvincia Autonoma di Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo report on the relation between home mould and/or dampness exposure and respiratory disorders in a large sample of children and adolescents in Italy, accounting for age at time of exposure.

methods20,016 children (mean age 7 years) and 13,266 adolescents (mean age 13 years) completed questionnaires on indoor exposures and respiratory symptoms/diseases. Statistical analyses were adjusted for sex, age, questionnaire's compiler, area of residence, season of interview, parental educational status, family history of asthma, rhinitis, eczema, chronic obstructive pulmonary disease, presence of gas water heaters, passive smoking, pets, and active smoking (only for adolescents). Population attributable risk % (PAR) was also computed.

resultsAsthma was more strongly related to only early than to only current exposure, both in children (OR 1.80, 95% CI 1.41 to 2.30) and adolescents (OR 1.89, 95% CI 1.38 to 2.59). The same result was found for rhino-conjunctivitis (OR 1.46, 95% CI 1.17 to 1.82), in children, and for wheeze among adolescents (OR 1.56, 95% CI 1.15 to 2.11). In children, wheeze (OR 1.98, 95% CI 1.47 to 2.66) and eczema (OR 1.44, 95% CI 1.09 to 1.91) were more strongly related to mould/dampness when exposed both early and currently; the same occurred in adolescents for rhino-conjunctivitis (1.78, 95% CI 1.30 to 2.45). Although persistent cough/phlegm was significantly related to mould/dampness exposure in children, regardless of exposure timing, no significant association between mould/dampness exposure and eczema or cough/phlegm was found among adolescents. PAR estimates were higher for only early than only current exposures. Avoiding early only exposure would abate wheeze by 6%, asthma or cough/phlegm by 7%, rhino-conjunctivitis in children by 4%, and in adolescents, asthma by 6%, and wheeze by 4%.

conclusionsRespiratory disorders such as wheeze and asthma can often be explained by exposure to home mould/dampness, especially early in life. The association seems more evident in children than in adolescents. These findings may suggest the need for environmental prevention strategies.

Indexed as

FungiAdolescentAge of OnsetChildEducational StatusEnvironmental ExposureFemaleHousingHumansHumidityItalyMalePrevalenceRegression AnalysisRespiration DisordersRisk Factors

Identifiers

PMID16109818
PMCPMC1741087
OpenAlexW2129947183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.