Trial reportJournal of perinatology : official journal of the California Perinatal Association2005
A randomized multicenter study to determine the efficacy of activity restriction for preterm labor management in patients testing negative for fetal fibronectin.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Society for Maternal-Fetal Medicine Consult Series #50: The role of activity restriction in obstetric management: (Replaces Consult Number 33, August 2014).American journal of obstetrics and gynecology · 2020Guideline
- Fetal fibronectin testing for reducing the risk of preterm birth.The Cochrane database of systematic reviews · 2019Pooled it
- Bed rest in singleton pregnancies for preventing preterm birth.The Cochrane database of systematic reviews · 2015Pooled it
- Fetal fibronectin testing for reducing the risk of preterm birth.The Cochrane database of systematic reviews · 2008Pooled it
- Impact of Physical Activity Interventions on High-Risk Pregnancies: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2023Review
- Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry Number 015/025, February 2019) - Part 2 with Recommendations on the Tertiary Prevention of Preterm Birth and the Management of Preterm Premature Rupture of Membranes.Geburtshilfe und Frauenheilkunde · 2019Article
- Changing prevalence and the risk factors for antenatal obstetric hospitalizations in Denmark 2003-2012.Clinical epidemiology · 2016Article
- Activity in Pregnancy for Patients with a History of Preterm Birth.Clinical medicine insights. Women's health · 2016Article
- Activity restriction among women with a short cervix.Obstetrics and gynecology · 2013Article
- Lack of evidence for prescription of antepartum bed rest.Expert review of obstetrics & gynecology · 2011Article
- Prenatal bed rest in developed and developing regions: a systematic review and meta-analysis.CMAJ openArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the impact of activity restriction (AR) on the incidence of preterm birth in women treated for preterm labor testing negative for fetal fibronectin (fFN). STUDY
designWomen who were diagnosed with preterm labor and tocolyzed with magnesium sulfate were concurrently screened with fFN for the purpose of subsequent management. Included were consenting patients with negative fFN, gestational age 23 0/7-33 6/7 weeks, cervical dilation < or =3 cm, and minimal vaginal bleeding. Patients were randomized to AR or no AR. Primary study outcome was incidence of preterm delivery and interval from randomization to delivery.
resultsA total of 73 women with negative fFN were randomized (36 with AR, 37 without AR). The overall preterm birth rate was 40%, with 44.4% of patients with AR and 35.1% of patients without AR delivering preterm, p=0.478.
conclusionMaternal AR did not impact pregnancy outcome. The incidence of preterm birth in symptomatic women testing fFN negative was higher than previously reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.