Evidence map›Paper›PMID 16106080›Full record

ReviewImmunologic research2005

Immune regulation of viral infection and vice versa.

Herbert W Virgin

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The role of infectious agents in the pathogenesis of vasculitis.Best practice & research. Clinical rheumatology · 2008
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Herbert W VirginDepartment of Pathology and Immunology, Center for Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. virgin@wustl.edu
Washington University in St. Louis · US

Funding

IMMUNITY AND PATHOGENESIS OF A NOVEL NOROVIRUSR01AI054483 · NIAID · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 2003 to 2012
$3.7M
Regulation of Y-herpesvirus latency and tumorigenesisR01CA074730 · NCI · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 1998 to 2007
$2.8M
Vascular Injury and Atherosclerosis During Herpesvirus *R01HL060090 · NHLBI · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 1999 to 2005
$2.5M
T Cell Vaccination Against gamma-herpesvirus LatencyR01CA096511 · NCI · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 2002 to 2012
$2.4M
MECHANISM OF GAMMA-HERPESVIRUS DAF/MCP HOMOLOGR01AI045019 · NIAID · WASHINGTON UNIVERSITY · PI VIRGIN, HERBERT W · 2000 to 2004
$1.7M
NCI NIH HHS R01 CA74730NCI NIH HHS R01 CA96511NHLBI NIH HHS R01 HL60090NIAID NIH HHS R01 AI45019NIAID NIH HHS R01 AI54483
6 · The paper itself

Abstract

In our laboratory we study the mechanisms by which the immune system controls viral infection and by which viruses evade immune control. To study issues at this interface between virology and immunology, we work from the hypothesis that viruses manipulate the immune response as the immune response attempts to eradicate the virus. Analysis of these issues is key to understanding acute and chronic diseases caused by viruses. Two concepts drive our approach: (1) the simultaneous analysis of immune and viral mechanisms allows novel insights, and (2) genetic tests in vivo are necessary to establish mechanisms.

Indexed as

AnimalsCaliciviridae InfectionsDendritic CellsGammaherpesvirinaeGenes, ViralHerpesviridae InfectionsHumansMacrophagesMiceNorovirusT-Lymphocyte SubsetsViral VaccinesVirus DiseasesVirus LatencyVirus ReplicationViral Vaccines

Identifiers

PMID16106080
OpenAlexW2002964341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.