ReviewImmunologic research2005
Understanding the pathogenesis of psoriasis, psoriatic arthritis, and autoimmunity via a fusion of molecular genetics and immunology.
Review in Immunologic research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Addictive behaviors, cardiovascular and metabolic comorbidities in North African psoriatic patients: case-control study.The Pan African medical journal · 2019Article
- Psoriasis: Obesity and Fatty Acids.Frontiers in immunology · 2019Review
- Serum prolactin levels in psoriasis vulgaris.ISRN dermatology · 2014Article
- Computational approach to identify enzymes that are potential therapeutic candidates for psoriasis.Enzyme research · 2011Article
- The relation between different dimensions of alcohol consumption and burden of disease: an overview.Addiction (Abingdon, England) · 2010Article
- Prevalence of autoantibodies in patients of psoriasis.Journal of clinical laboratory analysis · 2010Article
- Infliximab (Remicade) in the treatment of psoriatic arthritis.Therapeutics and clinical risk management · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The goal of my laboratory is to understand the molecular genetics basis of the inflammatory skin disease psoriasis and associated psoriatic arthritis. In performing these studies my colleagues and I have begun to identify common pathways leading to autoimmunity as well, because some of the defective pathways leading to autoimmunity are the same in different autoimmune diseases. Some of these pathways are involved in determining the activation status of inflammatory cells in the resting state. Other pathways are likely to determine target organ specificity and will be unique to a particular disease. Our approaches rely on genetic studies with cases and families to identify the causative variants, and then functional studies to identify the role of these variants in the predisposition to psoriasis and autoimmunity. The advantage of genetics approaches to understanding diseases such as those of the immune system is that one can identify novel genes and pathways that were not previously suspected as being involved in either the immune system or tolerance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.