Evidence map›Paper›PMID 16106031›Full record

ArticlePhysiological genomics2005

Tools and strategies for physiological genomics: the Rat Genome Database.

Simon N Twigger, Dean Pasko, Jeff Nie, Mary Shimoyama, Susan Bromberg, Dan Campbell, Jiali Chen, Norberto dela Cruz, Chunyu Fan, Cindy Foote and 22 more

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Description of International Caenorhabditis elegans Experiment first flight (ICE-FIRST).Advances in space research : the official journal of the Committee on Space Research (COSPAR) · 2008
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 1 institution in 1 country.

Simon N TwiggerHuman and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Dean Pasko
Jeff Nie
Mary Shimoyama
Susan Bromberg
Dan Campbell
Jiali Chen
Norberto dela Cruz
Chunyu Fan
Cindy Foote
Glenn Harris
Brian Hickmann
Yuan Ji
Weihong Jin
Dawei Li
Jedidiah Mathis
Nataliya Nenasheva
Rajni Nigam
Victoria Petri
Dorothy Reilly
Victor Ruotti
Eric Schauberger
Kathy Seiler
Ronit Slyper
Jennifer Smith
Weiye Wang
Wenhua Wu
Lan Zhao
Angela Zuniga-Meyer
Peter J Tonellato
Anne E Kwitek
Howard J Jacob
Medical College of Wisconsin · US

Funding

RAT GENOME DATABASER01HL064541 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ANNE E. KWITEK · 1999 to 2026
$50.0M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Gene Ontology ConsortiumP41HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2004 to 2011
$27.4M
SCOR-MOLECULAR GENTICS OF HYPERTENSIONP50HL054998 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI COWLEY, ALLEN W · 1996 to 2005
$8.1M
GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
NHGRI NIH HHS HG-002273NHGRI NIH HHS P41 HG002273NHGRI NIH HHS R01 HG002273NHGRI NIH HHS U41 HG002273NHLBI NIH HHS HL-64541NHLBI NIH HHS P50 HL054998NHLBI NIH HHS R01 HL064541
6 · The paper itself

Abstract

The broad goal of physiological genomics research is to link genes to their functions using appropriate experimental and computational techniques. Modern genomics experiments enable the generation of vast quantities of data, and interpretation of this data requires the integration of information derived from many diverse sources. Computational biology and bioinformatics offer the ability to manage and channel this information torrent. The Rat Genome Database (RGD; http://rgd.mcw.edu) has developed computational tools and strategies specifically supporting the goal of linking genes to their functional roles in rat and, using comparative genomics, to human and mouse. We present an overview of the database with a focus on these unique computational tools and describe strategies for the use of these resources in the area of physiological genomics.

Indexed as

Databases, GeneticAnimalsCloning, MolecularGene Expression ProfilingGenomeGenomicsRats

Identifiers

PMID16106031
PMCPMC4505745
OpenAlexW2144813793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.