ArticleHeart (British Cardiac Society)2005
Cardiovascular risk factors and clinical presentation in acute coronary syndromes.
Article in Heart (British Cardiac Society), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 80 citations in OpenAlex.
- Circulating exosomal miRNA in acute coronary syndrome: mechanisms, clinical relevance and future directions.Frontiers in molecular biosciences · 2026Review
- Development and validation of identification models for aortic dissection and non-ST-segment elevation acute coronary syndrome in the emergency department.Scientific reports · 2025Article
- 10-year cardiovascular disease risk and its predictors: a comparison between healthcare workers and the general public in Qatar.BMC public health · 2025Article
- Association Between Shift Work and Acute Coronary Syndrome According to Alcohol Intake and Smoking.Medicina (Kaunas, Lithuania) · 2025Article
- Correlation of Plasmatic Amyloid Beta Peptides (Aβ-40, Aβ-42) with Myocardial Injury and Inflammatory Biomarkers in Acute Coronary Syndrome.Journal of clinical medicine · 2024Article
- Wellens Syndrome: prevalence, risk factors and coronary angiographic variation. A cross-sectional study.BMC cardiovascular disorders · 2024Observational
- Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis.Journal of pharmaceutical policy and practice · 2023Review
- Predictors of Readmission after the First Acute Coronary Syndrome and the Risk of Recurrent Cardiovascular Events-Seven Years of Patient Follow-Up.Life (Basel, Switzerland) · 2023Article
- Gender differences in prevalence of myocardial infarction in rural West Texans.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022Article
- Association of major cardiovascular risk factors with the development of acute coronary syndrome in Lithuania.European heart journal supplements : journal of the European Society of Cardiology · 2014Article
- Prevalence of conventional risk factors and lipid profiles in patients with acute coronary syndrome and significant coronary disease.Therapeutics and clinical risk management · 2014Article
- Article
- Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: data from a multicentre registry.Cardiovascular journal of Africa · 2012Article
- The importance of diabetes mellitus in the global epidemic of cardiovascular disease: the case of the state of Qatar.Transactions of the American Clinical and Climatological Association · 2012Article
- Prevalence and impact of cardiovascular risk factors among patients presenting with acute coronary syndrome in the middle East.Clinical cardiology · 2011Article
- Effect of smoking on age at the time of coronary artery bypass graft surgery; baseline data results from the ROSETTA-CABG registry.Heart Asia · 2010Article
- Declining case fatality rates for acute myocardial infarction in South Asian and white patients in the past 15 years.Heart (British Cardiac Society) · 2006Article
- Regionalization of ST-segment elevation acute coronary syndromes care: putting a national policy in proper perspective.Journal of the American College of Cardiology · 2006Review
- The declining prevalence of ST elevation myocardial infarction in patients presenting with acute coronary syndromes.Heart (British Cardiac Society) · 2005Article
- Risk profile and in-hospital prognosis in elderly patients presenting for acute ST-elevation myocardial infarction in the Tunisian context.Indian heart journalArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the hypothesis that risk factors may be differently related to severity of acute coronary syndromes (ACS), with ST elevation used as a marker of severe ACS.
designCross sectional study of patients with ACS.
setting103 hospitals in 25 countries in Europe and the Mediterranean basin. PATIENTS: 10,253 patients with a discharge diagnosis of ACS in the Euro heart survey of ACS.
main outcome measuresPresenting with ST elevation ACS.
resultsPatients with ACS who were smokers had an increased risk to present with ST elevation (age adjusted odds ratio (OR) 1.84, 95% confidence interval (CI) 1.67 to 2.02). Hypertension (OR 0.65, 95% CI 0.60 to 0.70) and high body mass index (BMI) (p for trend 0.0005) were associated with less ST elevation ACS. Diabetes mellitus was also associated with less ST elevation, but only among men. Prior disease (infarction, chronic angina, revascularisation) and treatment with aspirin, beta blockers, or statins before admission were also associated with less ST elevation. After adjustment for age, sex, prior disease, and prior medication, smoking was still significantly associated with increased risk of ST elevation (OR 1.53, 95% CI 1.38 to 1.69), whereas hypertension was associated with reduced risk (OR 0.75, 95% CI 0.69 to 0.82). Obesity (BMI > 30 kg/m2 versus < 25 kg/m2) was independently associated with less risk of presenting with ST elevation among women, but not among men.
conclusionAmong patients with ACS, presenting with ST elevation is strongly associated with smoking, whereas hypertension and high BMI (in women) are associated with less ST elevation, independently of prior disease and medication.
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