Evidence map›Paper›PMID 16102655›Full record

ReviewInfectious disease clinics of North America2005

The link between bronchiolitis and asthma.

Tuomas Jartti, Mika J Mäkelä, Timo Vanto, Olli Ruuskanen

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Infectious disease clinics of North America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01098227 (A Prospective Study Measuring Exhaled Nitric Oxide Levels in Infants and Young Children Admitted to the Hospital for Respiratory Syncytial Virus), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01098227 withdrawnnot on this mapstarted 2010, after this paper: background citation

A Prospective Study Measuring Exhaled Nitric Oxide Levels in Infants and Young Children Admitted to the Hospital for Respiratory Syncytial Virus (RSV) or Other Viral Lower Respiratory Tract Infections

TypeobservationalSponsorNYU Langone HealthRan2010 to 2011Enrolled0ConditionsBronchiolitis, Infection, Nitric Oxide
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Efficacy of prednisolone in children hospitalized for recurrent wheezing.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2007
    Trial
  2. Early-life respiratory syncytial virus infection and asthma.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Racial and ethnic disparities in bronchiolitis management in freestanding children's hospitals.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021
    Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Wheezing in infancy.The World Allergy Organization journal · 2011
    Article
  15. Antimicrobial therapy in childhood asthma and wheezing.Treatments in respiratory medicine · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tuomas JarttiDepartment of Pediatrics, Turku University Hospital, Finland.
Mika J Mäkelä
Timo Vanto
Olli Ruuskanen
Turku University Hospital · FIHelsinki University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiolitis and asthma are common wheezing illnesses of childhood. Respiratory syncytial virus is the main causative agent of Bronchiolitis. Rhinovirus is the most common trigger of exacerbations of asthma, but also has been detected increasingly in doing children with Bronchiolitis. Reportedly, childhood asthma develops in 40% of children with a history of Bronchiolitis. No convincing link has been reported between Bronchiolitis and development of atopy, although atopy generally is regarded as the main risk factor for chronic asthma. This article focuses on the association between bronchiolitis and the development of asthma. The authors address the question how respiratory syncytial virus and rhinovirus infections in young children, together with genetics and immunologic immaturity, may contribute to the development of asthma.

Indexed as

AdolescentAsthmaBronchial HyperreactivityBronchiolitisChildChild, PreschoolHumansHypersensitivity, ImmediateInfantPicornaviridae InfectionsRespiratory Syncytial Virus Infections

Identifiers

PMID16102655
PMCPMC7118846
OpenAlexW2136838229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.