ArticleNeuron2005
Contrast adaptation and representation in human early visual cortex.
Article in Neuron, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
118 citing papers in PubMed, 213 citations in OpenAlex.
- Efficient measurements for the dynamic range of human lightness perception.Japanese journal of ophthalmology · 2021Trial
- Occipital transcranial magnetic stimulation has an activity-dependent suppressive effect.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Trial
- Visual Responsivity in Autism: Measuring Visual Responses in Autistic and Non-Autistic Adults Using Psychophysics, fMRI, and EEG.Autism research : official journal of the International Society for Autism Research · 2026Article
- Model-based estimation of the population contrast response function in human visual cortex.Journal of vision · 2026Article
- The Human Visual Claustrum Responses to Physical Stimulus Properties and Subjective Content During Movie Viewing.Human brain mapping · 2026Article
- Covert spatial attention is uniform across cardinal meridians despite differential adaptation.Journal of vision · 2026Article
- Covert spatial attention is uniform across cardinal meridians despite differential adaptation.bioRxiv : the preprint server for biology · 2025Article
- Two opposing yet complementary ocular dominance plasticities: thalamus strengthens the weak channel while higher cortex listens to the strong signal.Communications biology · 2025Article
- Early Visual Cortex Supports One-Shot Episodic Memory via Spatially Tuned Reactivation.bioRxiv : the preprint server for biology · 2025Article
- Effects of brief and prolonged blur adaptation on visual search and discrimination.Vision research · 2025Article
- Visual adaptation stronger at the horizontal than the vertical meridian: Linking performance with V1 cortical surface area.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Heterogeneous Effects of Cognitive Arousal on the Contrast Response in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Guided visual search is associated with target boosting and distractor suppression in early visual cortex.Communications biology · 2025Article
- Impact of Rod-Dominant Mesopic Conditions on Spatial Summation and Surround Suppression in Early Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- How does orientation-tuned normalization spread across the visual field?Journal of neurophysiology · 2025Article
- Ocular Dominance Plasticity: A Mini-Review.Eye and brain · 2025Review
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- Temporal regularities shape perceptual decisions and striatal dopamine signals.Nature communications · 2024Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
The human visual system can distinguish variations in image contrast over a much larger range than measurements of the static relationship between contrast and response in visual cortex would suggest. This discrepancy may be explained if adaptation serves to re-center contrast response functions around the ambient contrast, yet experiments on humans have yet to report such an effect. By using event-related fMRI and a data-driven analysis approach, we found that contrast response functions in V1, V2, and V3 shift to approximately center on the adapting contrast. Furthermore, we discovered that, unlike earlier areas, human V4 (hV4) responds positively to contrast changes, whether increments or decrements, suggesting that hV4 does not faithfully represent contrast, but instead responds to salient changes. These findings suggest that the visual system discounts slow uninformative changes in contrast with adaptation, yet remains exquisitely sensitive to changes that may signal important events in the environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.