ReviewEmerging infectious diseases2005
Laboratory exposures to brucellae and implications for bioterrorism.
Review in Emerging infectious diseases, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Evaluation of immune responses toFrontiers in veterinary science · 2022Pooled it
- Global Comprehensive Literature Review and Meta-Analysis of Brucella spp. in Swine Based on Publications From 2000 to 2020.Frontiers in veterinary science · 2021Pooled it
- Occupational exposure to Brucella spp.: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2020Pooled it
- Brucellosis in the One Health Context: Gaps in Diagnosis, Control, and Global Epidemiology.Journal of epidemiology and global health · 2026Review
- A 3D Organotypic Human Bronchial Model Reveals Persistent Infection and Modulated Inflammatory Response when Exposed toTropical medicine and infectious disease · 2026Article
- First isolation and molecular confirmation of Brucella canis in dogs from Egypt.BMC microbiology · 2026Article
- Article
- Development of a rapid and sensitive RPA-CRISPR/Cas12a-based assay for the detection ofMicrobiology spectrum · 2025Article
- A case of hepatic-splenic abscess in a non-endemic area of brucellosis: insights from complex infection with brucellosis.BMC infectious diseases · 2025Article
- Ultrasensitive and highly specific detection of theJournal of clinical microbiology · 2025Article
- Brucellosis: Unveiling the complexities of a pervasive zoonotic disease and its global impacts.Open veterinary journal · 2024Review
- Role of the cGAS/STING pathway in the control ofFrontiers in immunology · 2023Article
- A follow-up study of 100 patients with acute brucellosis for its prognosis and prevention.Frontiers in medicine · 2023Article
- A systematic analysis of and recommendations for public health events involving brucellosis from 2006 to 2019 in China.Annals of medicine · 2022Article
- Immunization with a combination of recombinant Brucella abortus proteins induces T helper immune response and confers protection against wild-type challenge in BALB/c mice.Microbial biotechnology · 2022Article
- Cross-Sectional Study of Seroprevalence and Associated Risk Factors of Bovine Brucellosis in Selected Districts of Jimma Zone, South Western Oromia, Ethiopia.BioMed research international · 2022Article
- Article
- Microbiological Laboratory Diagnosis of Human Brucellosis: An Overview.Pathogens (Basel, Switzerland) · 2021Review
- Biowarfare, bioterrorism and biocrime: A historical overview on microbial harmful applications.Forensic science international · 2020Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brucellae are class 3 organisms and potential agents of bioterrorism. Because of effective public health measures, brucellosis has become a rare disease in industrialized countries, and clinical microbiology laboratories are frequently unfamiliar with the genus. A low index of suspicion by physicians or failure to notify the laboratory, equivocal Gram-stain results, misidentification of the organism by commercial systems, unsafe laboratory practices, and laboratory accidents have been responsible for numerous cases of exposure to the organism and laboratory-acquired disease in recent years. Discovery of a laboratory exposure to brucellae should prompt an exhaustive investigation of the event and its circumstances, definition of the population at risk, enforcement of safe laboratory practices, and antimicrobial drug prophylaxis for exposed persons. Inadvertent exposures to brucellae in the clinical laboratory indicate a widespread lack of preparedness to cope with eventual biologic threats involving use of the organism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.