ArticleJournal of the American Society for Mass Spectrometry2005
Peptide mass mapping of acetylated isoforms of histone H4 from mouse lymphosarcoma cells treated with histone deacetylase (HDACs) inhibitors.
Article in Journal of the American Society for Mass Spectrometry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
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- Spinal Muscular Atrophy Biomarker Measurements from Blood Samples in a Clinical Trial of Valproic Acid in Ambulatory Adults.Journal of neuromuscular diseases · 2015Article
- Histone H1 phosphorylation in breast cancer.Journal of proteome research · 2014Article
- Isolation and analysis of linker histones across cellular compartments.Journal of proteomics · 2013Article
- Characterising microbial protein test substances and establishing their equivalence with plant-produced proteins for use in risk assessments of transgenic crops.Transgenic research · 2013Article
- Apigenin induces DNA damage through the PKCδ-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair.Biochemical pharmacology · 2012Article
- High-sensitivity TFA-free LC-MS for profiling histones.Proteomics · 2011Article
- Age-related changes in mesenchymal stem cells derived from rhesus macaque bone marrow.Aging cell · 2011Article
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- Assaying pharmacodynamic endpoints with targeted therapy: flavopiridol and 17AAG induced dephosphorylation of histone H1.5 in acute myeloid leukemia.Proteomics · 2010Article
- Unambiguous determination of isobaric histone modifications by reversed-phase retention time and high-mass accuracy.Analytical biochemistry · 2010Article
- Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing.Chemistry & biology · 2009Article
- Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009Article
- Validation of an LC-MS based approach for profiling histones in chronic lymphocytic leukemia.Proteomics · 2009Article
- MassMatrix: a database search program for rapid characterization of proteins and peptides from tandem mass spectrometry data.Proteomics · 2009Article
- Unraveling the histone's potential: a proteomics perspective.Epigenetics · 2008Article
- Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos.Developmental biology · 2008Article
- Identification of histone demethylases in Saccharomyces cerevisiae.The Journal of biological chemistry · 2007Article
- Liquid chromatography mass spectrometry profiling of histones.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2007Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The acetylated isoforms of histone H4 from mouse lymphosarcoma cells treated with HDAC inhibitors trichostatin A (TSA) and depsipeptide (DDP) were separated by acetic acid urea-polyacrylamide gel electrophoresis (AU-PAGE), in-gel digested, and analyzed by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and liquid chromatography tandem mass spectrometry (LC-MS/MS). The acetylation pattern of histone H4 in mouse lymphosarcoma cells induced by TSA was established in which acetylation initially occurred at K16 followed by K12 and then K8 and/or K5. An identical order of acetylation was found for cells treated with DDP.
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