Evidence map›Paper›PMID 16093798›Full record

ReviewCurrent opinion in oncology2005

Human T cell lymphotropic virus-associated leukemia/lymphoma.

Lee Ratner

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in oncology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lee RatnerDivision of Molecular Oncology, Washington University, 660 South Euclid Avenue, Saint Louis, MO 63110, USA. lratner@im.wustl.edu
Molecular Oncology (United States) · US

Funding

Role of Inflammation in Tax-mediated TumorigenesisP01CA100730 · NCI · WASHINGTON UNIVERSITY · PI Malachi Griffith · 2003 to 2026
$44.8M
PROLIFERATIVE EFFECTS OF HTLV1R01CA063417 · NCI · WASHINGTON UNIVERSITY · PI RATNER, LEE · 1995 to 2017
$3.7M
AIDS-ASSOCIATED MALIGNANCIES CLINICAL TRIALS MEMBERU01CA070062 · NCI · NORTHWESTERN UNIVERSITY · PI VON ROENN, JAMIE H · 1995 to 2005
$1.3M
Chemo/Antiretroviral therapy for HTLV-1 ATLLR01CA105218 · NCI · WASHINGTON UNIVERSITY · PI RATNER, LEE · 2003 to 2005
$681k
CHEMO/ANTIRETROVIRAL THERAPY FOR HTLV1 ATLLR21CA093062 · NCI · WASHINGTON UNIVERSITY · PI RATNER, LEE · 2001 to 2002
$608k
NCI NIH HHS CA 10073NCI NIH HHS CA 105218NCI NIH HHS CA 63417NCI NIH HHS CA 70062NCI NIH HHS P01 CA100730NCI NIH HHS R01 CA063417NCI NIH HHS R01 CA105218NCI NIH HHS R21 CA093062NCI NIH HHS U01 CA070062
6 · The paper itself

Abstract

purpose of reviewThis article summarizes the current pathophysiologic basis for human T cell lymphotropic virus-associated leukemia/lymphoma as well as past, present, and future therapeutic options. RECENT

findingsNew studies have been published on allogeneic stem cell transplantation, arsenic trioxide, and bortezomib for this condition. SUMMARY: Studies of the molecular biology of human T cell lymphotropic virus-1-induced T cell leukemia/lymphoma have defined a critical role for oncoprotein, Tax, and activation of nuclear factor kappaB transcription pathways, which have provided rational approaches to improved therapy for T cell leukemia/lymphoma as well as a model for other hematopoietic malignancies characterized by nuclear factor kappaB activation.

Indexed as

AntibodiesAntineoplastic AgentsAnti-Retroviral AgentsDeltaretrovirus AntibodiesHumansHuman T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellLymphoma, T-CellPrognosisStem Cell TransplantationAntibodiesAntineoplastic AgentsAnti-Retroviral AgentsDeltaretrovirus Antibodies

Identifiers

PMID16093798
PMCPMC2652726
OpenAlexW1988711830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.