Evidence map›Paper›PMID 16093685›Full record

ReviewCytogenetic and genome research2005

Transposable elements donate lineage-specific regulatory sequences to host genomes.

L Mariño-Ramírez, K C Lewis, D Landsman, I K Jordan

Open access · bronzeAbstract readReview
In one paragraph

Review in Cytogenetic and genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
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  4. An atlas of transposable element-derived alternative splicing in cancer.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Article
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  11. Article
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  13. Article
  14. Review
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  16. Retrotransposon-associated long non-coding RNAs in mice and men.Pflugers Archiv : European journal of physiology · 2016
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

L Mariño-RamírezNational Center for Biotechnology Information, National Institutes of Health, Bethesda, MD 20894, USA.
K C Lewis
D Landsman
I K Jordan
National Institutes of Health · USUniversity of North Carolina at Chapel Hill · US

Funding

Gene Regulatory Sequences from Whole Chromosomes/genomesZ01LM000084 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LANDSMAN, DAVID · 1998 to 2008
$627k
Analysis Of Repeated Elements In The Human GenomeZ01LM000092 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LANDSMAN, DAVID · 2001 to 2006
–
Intramural NIH HHS Z99 LM999999
6 · The paper itself

Abstract

The evolutionary implications of transposable element (TE) influences on gene regulation are explored here. An historical perspective is presented to underscore the importance of TE influences on gene regulation with respect to both the discovery of TEs and the early conceptualization of their potential impact on host genome evolution. Evidence that points to a role for TEs in host gene regulation is reviewed, and comparisons between genome sequences are used to demonstrate the fact that TEs are particularly lineage-specific components of their host genomes. Consistent with these two properties of TEs, regulatory effects and evolutionary specificity, human-mouse genome wide sequence comparisons reveal that the regulatory sequences that are contributed by TEs are exceptionally lineage specific. This suggests a particular mechanism by which TEs may drive the diversification of gene regulation between evolutionary lineages.

Indexed as

DNA Transposable ElementsAnimalsBase SequenceGenomeHumansMolecular Sequence DataRegulatory Sequences, Nucleic AcidSequence AlignmentSequence Homology, Nucleic AcidDNA Transposable Elements

Identifiers

PMID16093685
PMCPMC1803082
OpenAlexW2128663622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.