ArticleCytogenetic and genome research2005
HeT-A and TART, two Drosophila retrotransposons with a bona fide role in chromosome structure for more than 60 million years.
Article in Cytogenetic and genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Near complete assembly of Drosophila melanogaster Canton S strain genome.Nature communications · 2025Article
- A function of Spalt proteins in heterochromatin organization and maintenance of genomic DNA integrity.Development (Cambridge, England) · 2025Article
- Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species.Mobile DNA · 2023Article
- Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms.PloS one · 2019Article
- Drosophila: Retrotransposons Making up Telomeres.Viruses · 2017Review
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- HeT-A_pi1, a piRNA target sequence in the Drosophila telomeric retrotransposon HeT-A, is extremely conserved across copies and species.PloS one · 2012Article
- The chromosomal proteins JIL-1 and Z4/Putzig regulate the telomeric chromatin in Drosophila melanogaster.PLoS genetics · 2012Article
- Transcriptional analysis of the HeT-A retrotransposon in mutant and wild type stocks reveals high sequence variability at Drosophila telomeres and other unusual features.BMC genomics · 2011Article
- Single- and double-stranded DNA binding proteins act in concert to conserve a telomeric DNA core sequence.Genome integrity · 2011Article
- Evolution of diverse mechanisms for protecting chromosome ends by Drosophila TART telomere retrotransposons.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Small RNA-based silencing strategies for transposons in the process of invading Drosophila species.RNA (New York, N.Y.) · 2010Article
- Evolution of species-specific promoter-associated mechanisms for protecting chromosome ends by Drosophila Het-A telomeric transposons.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
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- Transcription and activation under environmental stress of the complex telomeric repeats of Chironomus thummi.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2008Article
- Intracellular targeting of telomeric retrotransposon Gag proteins of distantly related Drosophila species.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline.Nucleic acids research · 2007Article
- Canonical TTAGG-repeat telomeres and telomerase in the honey bee, Apis mellifera.Genome research · 2006Article
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Drosophila telomeres have been maintained by retrotransposition for at least 60 MY, which predates the separation of extant species of this genus. Studies of D. melanogaster, D. yakuba, and D. virilis show that, in Drosophila, telomeres are composed of two non-LTR retrotransposons, HeT-A and TART. Far from being static, HeT-A and TART evolve faster than Drosophila euchromatic genes. In spite of their high rate of sequence change, HeT-A and TART maintain their basic structures and unusual individual features. The maintenance of their separate identities suggests that HeT-A and TART cooperate either in the process of retrotransposition onto the chromosome end, or in the formation of telomere chromatin by transposed DNA copies. The telomeric retrotransposons and the Drosophila genome constitute an example of a robust symbiotic relationship between mobile elements and the genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.