ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2005
Abrupt maturation of a spike-synchronizing mechanism in neocortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 86 citations in OpenAlex.
- Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response.Molecular psychiatry · 2026Article
- Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex.eNeuro · 2024Article
- Neural activity responsiveness by maturation of inhibition underlying critical period plasticity.Frontiers in neural circuits · 2024Article
- Function and Plasticity of Electrical Synapses in the Mammalian Brain: Role of Non-Junctional Mechanisms.Biology · 2022Review
- The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth.Frontiers in integrative neuroscience · 2022Article
- AnFrontiers in neural circuits · 2021Article
- Adolescence as a neurobiological critical period for the development of higher-order cognition.Neuroscience and biobehavioral reviews · 2018Review
- A neural circuit for gamma-band coherence across the retinotopic map in mouse visual cortex.eLife · 2018Article
- Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex.eLife · 2017Article
- Synchronized gamma-frequency inhibition in neocortex depends on excitatory-inhibitory interactions but not electrical synapses.Journal of neurophysiology · 2016Article
- Postnatal development of the electrophysiological properties of somatostatin interneurons in the anterior cingulate cortex of mice.Scientific reports · 2016Article
- Early Somatostatin Interneuron Connectivity Mediates the Maturation of Deep Layer Cortical Circuits.Neuron · 2016Article
- Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome.Neural plasticity · 2016Review
- H3 and H4 Lysine Acetylation Correlates with Developmental and Experimentally Induced Adult Experience-Dependent Plasticity in the Mouse Visual Cortex.Journal of experimental neuroscience · 2016Article
- The distinct role of NR2B subunit in the enhancement of visual plasticity in adulthood.Molecular brain · 2015Article
- Properties of precise firing synchrony between synaptically coupled cortical interneurons depend on their mode of coupling.Journal of neurophysiology · 2015Article
- Simulating vertical and horizontal inhibition with short-term dynamics in a multi-column multi-layer model of neocortex.International journal of neural systems · 2014Article
- The effects of postnatal exposure to low-dose bisphenol-A on activity-dependent plasticity in the mouse sensory cortex.Frontiers in neuroanatomy · 2014Article
- Hearing loss differentially affects thalamic drive to two cortical interneuron subtypes.Journal of neurophysiology · 2013Article
- Electrophysiological and morphological properties of neurons in layer 5 of the rat postrhinal cortex.Hippocampus · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Synchronous activity is common in the neocortex, although its significance, mechanisms, and development are poorly understood. Previous work showed that networks of electrically coupled inhibitory interneurons called low-threshold spiking (LTS) cells can fire synchronously when stimulated by metabotropic glutamate receptors. Here we found that the coordinated inhibition emerging from an activated LTS network could induce correlated spiking patterns among neighboring excitatory cells. Synchronous activity among LTS cells was absent at postnatal day 12 (P12) but appeared abruptly over the next few days. The rapid development of the LTS-synchronizing system coincided with the maturation of the inhibitory outputs and intrinsic membrane properties of the neurons. In contrast, the incidence and magnitude of electrical synapses remained constant between P8 and P15. The developmental transformation of LTS interneurons into a synchronous, oscillatory network overlaps with the onset of active somatosensory exploration, suggesting a potential role for this synchronizing system in sensory processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.