ArticleJournal of industrial microbiology & biotechnology2006
Genetic control for light-induced carotenoid production in non-phototrophic bacteria.
Article in Journal of industrial microbiology & biotechnology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- Illuminating the dark majority: photobiology of nonphotosynthetic bacteria.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Review
- Exploiting Bacterial Pigmentation for Non-Destructive Detection of Seed-Borne Pathogens by Using Photoacoustic Techniques.Sensors (Basel, Switzerland) · 2024Article
- Chromosome architecture as a determinant for biosynthetic diversity inMicrobial genomics · 2024Article
- Carotenoids produced by the deep-sea bacterium Erythrobacter citreus LAMA 915: detection and proposal of their biosynthetic pathway.Folia microbiologica · 2021Article
- Isolation and characterization of a heavy metal- and antibiotic-tolerant novel bacterial strain from a contaminated culture plate ofF1000Research · 2021Article
- Light Response ofJournal of bacteriology · 2020Article
- Light-inducible carotenoid production controlled by a MarR-type regulator in Corynebacterium glutamicum.Scientific reports · 2019Article
- Role and Function of Class III LitR, a Photosensor Homolog from Burkholderia multivorans.Journal of bacteriology · 2018Article
- Article
- Review
- MerR and ChrR mediate blue light induced photo-oxidative stress response at the transcriptional level in Vibrio cholerae.Scientific reports · 2017Article
- Isoprenoid Pyrophosphate-Dependent Transcriptional Regulation of Carotenogenesis inFrontiers in microbiology · 2017Article
- Role and Function of LitR, an Adenosyl B12-Bound Light-Sensitive Regulator of Bacillus megaterium QM B1551, in Regulation of Carotenoid Production.Journal of bacteriology · 2015Article
- Sioxanthin, a novel glycosylated carotenoid, reveals an unusual subclustered biosynthetic pathway.Environmental microbiology · 2015Article
- Nonphotosynthetic pigments as potential biosignatures.Astrobiology · 2015Article
- Changes in activity of metabolic and regulatory pathways during germination of S. coelicolor.BMC genomics · 2014Article
- Analysis of Carotenoid Production by Halorubrum sp. TBZ126; an Extremely Halophilic Archeon from Urmia Lake.Advanced pharmaceutical bulletin · 2014Article
- Blue and red light modulates SigB-dependent gene transcription, swimming motility and invasiveness in Listeria monocytogenes.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotenoids are naturally occurring yellow or orange pigments that serve as a protectant against photo-oxidative damages. Among the wide variety of producers, the prokaryotes generate a broad spectrum of carotenoids with diverse chemical structures that are expected to have a high potential in biotechnological applications. Bacterial carotenogenesis occurs in a constitutive or light-induced manner, which suggests the diversity of the regulatory mechanism. The mechanism for light-induced carotenoid production in non-phototrophic bacteria has been studied in detail in Myxococcus xanthus, a Gram-negative gliding bacterium. The complicated mechanism involves the activation of an extracytoplasmic function (ECF) sigma factor (CarQ), which leads to the sequestration of a MerR family transcriptional regulator (CarA) that represses the expression of the carotenoid biosynthesis genes in the dark. Recently, we identified another regulatory mechanism for light-induced carotenogenesis in Streptomyces coelicolor A3(2), a Gram-positive soil bacterium. In this organism, the transcription of the carotenoid biosynthesis gene cluster is specified by LitS, a photo-inducible ECF sigma factor. The evidence indicates that the photo-dependent transcription of litS is mediated by LitR, a MerR family transcriptional regulator. In addition, it is suggested that the conformational alteration of LitR upon receiving the illumination signal determines its binding to DNA. The carboxy-terminal domain of LitR contains a possible binding site for Vitamin B12, which may serve as a capturing apparatus for the illumination signal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.