Evidence map›Paper›PMID 16091249›Full record

ReviewCurrent HIV/AIDS reports2005

Primary human immunodeficiency virus type 1 infection.

Malini Soogoor, Eric S Daar

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00296660 (Acute HIV-1 Infection Prospective Cohort Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00296660 completednot on this mapstarted 2006, after this paper: background citation

Acute HIV-1 Infection Prospective Cohort Study

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2006 to 2013Enrolled1,300ConditionsHIV Infections
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Malini SoogoorDivision of HIV Medicine, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90502, USA.
Eric S Daar
UCLA Medical Center · US

Funding

ZONA-FREE HAMSTER OVA ASSAY AS AN INDICATOR OF MALE FERTILITYM01RR000425 · NCRR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ANDERSON, GAIL V · 1985 to 2011
$74.2M
Southern California Primary Infection ProgramU01AI043638 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RICHMAN, DOUGLAS D · 1998 to 2010
$21.3M
WOMEN'S HEALTH AGENDAU01AI027660 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CURRIER, JUDITH S. · 1988 to 2006
$11.8M
Pathogenesis of HIV and HCV in Hemophilia: HGDSR01HD041224 · NICHD · CHILDREN'S HOSPITAL LOS ANGELES · PI GOMPERTS, EDWARD DAVID · 2001 to 2004
$2.8M
NCRR NIH HHS RR00425NIAID NIH HHS AI27660NIAID NIH HHS AI43638NICHD NIH HHS HD41224
6 · The paper itself

Abstract

Primary human immunodeficiency virus type 1 (HIV-1) infection represents the initial stage of disease that immediately follows viral entry into the body. Primary infection is frequently accompanied by an acute retroviral syndrome with associated high levels of plasma HIV-1 RNA and the development of host immune responses. The identification of subjects during this period requires a high index of suspicion and an understanding of how to make the diagnosis, as standard HIV-1 antibody tests can initially be negative. Identifying these people provides a unique opportunity for early counseling to reduce further transmission, facilitates entry into care, and allows for further study of the immunopathogenesis of disease and the potential role of early antiretroviral therapy.

Indexed as

HIV-1HIV InfectionsAnti-Retroviral AgentsHumansRNA, ViralAnti-Retroviral AgentsRNA, Viral

Identifiers

PMID16091249
OpenAlexW1982474951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.