Trial reportMolecular psychiatry2005
Support for the association between the rare functional variant I425V of the serotonin transporter gene and susceptibility to obsessive compulsive disorder.
Trial report in Molecular psychiatry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The investigation of nonsynonymous SNPs of humanHeliyon · 2021Article
- Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits.Pharmacology & therapeutics · 2021Review
- Control of serotonin transporter phosphorylation by conformational state.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter.Scientific reports · 2016Article
- Insights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDAT.Frontiers in pharmacology · 2015Review
- Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome.Molecular autism · 2013Article
- Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.Movement disorders : official journal of the Movement Disorder Society · 2013Article
- Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- Olanzapine, but not fluoxetine, treatment increases survival in activity-based anorexia in mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- Role of mother's genes and environment in postpartum depression.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Myristoylation of cGMP-dependent protein kinase dictates isoform specificity for serotonin transporter regulation.The Journal of biological chemistry · 2011Article
- Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.Molecular psychiatry · 2011Article
- Genetics of obsessive-compulsive disorder.The Psychiatric clinics of North America · 2010Review
- Modeling rare gene variation to gain insight into the oldest biomarker in autism: construction of the serotonin transporter Gly56Ala knock-in mouse.Journal of neurodevelopmental disorders · 2009Article
- Assessing the validity of current mouse genetic models of obsessive-compulsive disorder.Behavioural pharmacology · 2009Review
- Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice.Biological psychiatry · 2009Article
- How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems.Neuropharmacology · 2008Review
- A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.Autism research : official journal of the International Society for Autism Research · 2008Article
- Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autism.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2008Article
- Serotonin transporter phosphorylation by cGMP-dependent protein kinase is altered by a mutation associated with obsessive compulsive disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.