Evidence map›Paper›PMID 16086854›Full record

ArticleGenome biology2005

Genome-wide promoter extraction and analysis in human, mouse, and rat.

Zhenyu Xuan, Fang Zhao, Jinhua Wang, Gengxin Chen, Michael Q Zhang

Abstract read
In one paragraph

Article in Genome biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. MicroRNA 195-5p TargetsInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenyu XuanCold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. xuan@cshl.edu
Fang Zhao
Jinhua Wang
Gengxin Chen
Michael Q Zhang

Funding

PROTEIN CODING GENES IN THE HUMAN GENOMER01HG001696 · NHGRI · UNIVERSITY OF TEXAS DALLAS · PI ZHANG, MICHAEL Q · 1997 to 2010
$5.1M
CANCER CLASSIFICATION BASED ON MRNA ISOFORMSR33CA088351 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI FU, XIANG-DONG · 2001 to 2003
$2.6M
Identification of novel genes in human genomeR01HG002600 · NHGRI · UNIVERSITY OF CHICAGO · PI WANG, SAN MING · 2003 to 2005
$1.7M
COMPUTATIONAL ANALYSIS OF GENOME EXPRESSION DATAR01GM060513 · NIGMS · COLD SPRING HARBOR LABORATORY · PI ZHANG, MICHAEL Q · 2000 to 2002
$898k
CANCER CLASSIFICATION BASED ON MRNA ISOFORMSR21CA088351 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI FU, XIANG-DONG · 2000 to 2000
$149k
NCI NIH HHS CA88351NCI NIH HHS R21 CA088351NCI NIH HHS R33 CA088351NHGRI NIH HHS HG002600NHGRI NIH HHS HG01696NHGRI NIH HHS R01 HG001696NHGRI NIH HHS R01 HG002600NIGMS NIH HHS GM60513NIGMS NIH HHS R01 GM060513
6 · The paper itself

Abstract

Large-scale and high-throughput genomics research needs reliable and comprehensive genome-wide promoter annotation resources. We have conducted a systematic investigation on how to improve mammalian promoter prediction by incorporating both transcript and conservation information. This enabled us to build a better multispecies promoter annotation pipeline and hence to create CSHLmpd (Cold Spring Harbor Laboratory Mammalian Promoter Database) for the biomedical research community, which can act as a starting reference system for more refined functional annotations.

Indexed as

AnimalsConserved SequenceCpG IslandsDatabases, GeneticGene Expression RegulationGenomeGenome, HumanHumansMiceOligonucleotide Array Sequence AnalysisPromoter Regions, GeneticRatsResearch DesignRNA, MessengerSensitivity and SpecificitySpecies SpecificityRNA, Messenger

Identifiers

PMID16086854
PMCPMC1273639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.