ReviewMedical microbiology and immunology2006
Apoptosis in infectious disease: how bacteria interfere with the apoptotic apparatus.
Review in Medical microbiology and immunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 59 citations in OpenAlex.
- Host cell death during infection with Chlamydia: a double-edged sword.FEMS microbiology reviews · 2021Review
- Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults.Cell death and differentiation · 2019Article
- Bacterial Heat Shock Protein GroEL (Hsp64) Exerts Immunoregulatory Effects on T Cells by Utilizing Apoptosis.PloS one · 2016Article
- Article
- Immunostimulation in the treatment for chronic fatigue syndrome/myalgic encephalomyelitis.Immunologic research · 2013Article
- Article
- Proteomic and bioinformatic profile of primary human oral epithelial cells.Journal of proteome research · 2012Article
- Role of apoptosis in disease.Aging · 2012Review
- Coxiella burnetii induces apoptosis during early stage infection via a caspase-independent pathway in human monocytic THP-1 cells.PloS one · 2012Article
- Lack of effective anti-apoptotic activities restricts growth of Parachlamydiaceae in insect cells.PloS one · 2012Article
- Measuring the physical cohesiveness of proteins using physical interaction enrichment.Bioinformatics (Oxford, England) · 2010Article
- Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.The Journal of biological chemistry · 2010Article
- Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells.Molecular oral microbiology · 2010Article
- Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis.The American journal of pathology · 2010Article
- Article
- Structures of the Shigella flexneri type 3 secretion system protein MxiC reveal conformational variability amongst homologues.Journal of molecular biology · 2008Article
- Staying alive: bacterial inhibition of apoptosis during infection.Trends in microbiology · 2008Review
- Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells.Journal of dental research · 2008Review
- Chlamydophila pneumoniae derived from inclusions late in the infectious cycle induce aponecrosis in human aortic endothelial cells.BMC microbiology · 2008Article
- Molecular mechanisms of host-pathogen interactions and their potential for the discovery of new drug targets.Current drug targets · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell death by apoptosis is a common response of a human cell to many extrinsic stimuli. A cell's sensitivity to apoptotic triggers is affected by its activation and differentiation status. Bacteria are recognised by cellular receptors and elicit a multitude of signal transduction events that can, among other effects, alter the cell's response towards apoptotic stimuli. Many different bacteria and bacterial products have been recognised as agents that can act in this way and either induce or inhibit cell death. Besides these common and, as we argue, indirect activities, chlamydiae have been described to have a more specific capacity. These specialists of intracellular life can directly attack the host cell's apoptotic pathway. Here, we will attempt to structure the field of bacterial inhibition of apoptosis and discuss recent advancements in our knowledge of how chlamydiae interfere with the host cell's capacity to undergo apoptosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.