Evidence map›Paper›PMID 16086162›Full record

ReviewPflugers Archiv : European journal of physiology2005

Viral evasion of the MHC class I antigen-processing machinery.

Sandra Loch, Robert Tampé

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Targeted degradation of ABC transporters in health and disease.Journal of bioenergetics and biomembranes · 2007
    Review
  10. Article
  11. Review
  12. Bats: important reservoir hosts of emerging viruses.Clinical microbiology reviews · 2006
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sandra LochInstitute of Biochemistry, Biocentre, J.W. Goethe-University Frankfurt, Marie-Curie-Str. 9, 60439 Frankfurt am Main, Germany.
Robert Tampé

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In their adaptation to the immune system in vertebrates, viruses have been forced to evolve elaborate strategies for evading the host's immune response. To ensure life-long persistence in the host, herpes viruses, adenoviruses and retroviruses have exploited multiple cellular pathways for their purpose, including the class I antigen-processing machinery. Attractive and prominent targets for viral attacks are the proteasome complex, the transporter associated with antigen processing, and MHC class I molecules. This review briefly outlines the different mechanisms of viral interference with the antigen-presentation pathway.

Indexed as

Virus Physiological PhenomenaAnimalsAntigen PresentationATP-Binding Cassette TransportersEndoplasmic Reticulum, RoughGenes, MHC Class IHerpesviridae InfectionsHistocompatibility Antigens Class IHumansProteasome Endopeptidase ComplexVirulence FactorsATP-Binding Cassette TransportersHistocompatibility Antigens Class IProteasome Endopeptidase Complextransporter associated with antigen processing (TAP)Virulence Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.