ArticleGenetics2005
Polymorphisms in cinnamoyl CoA reductase (CCR) are associated with variation in microfibril angle in Eucalyptus spp.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
63 citing papers in PubMed, 235 citations in OpenAlex.
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- Effects of Exogenous Ergothioneine onInternational journal of molecular sciences · 2023Article
- Toward the identification of molecular markers associated with phytochemical traits in the Iranian sumac (Food science & nutrition · 2021Article
- Development of a highly efficient 50K single nucleotide polymorphism genotyping array for the large and complex genome of Norway spruce (Picea abies L. Karst) by whole genome resequencing and its transferability to other spruce species.Molecular ecology resources · 2021Article
- Haplotype- and SNP-Based GWAS for Growth and Wood Quality Traits inPlants (Basel, Switzerland) · 2021Article
- Dissection of Allelic Variation Underlying Floral and Fruit Traits in Flare Tree Peony (Frontiers in genetics · 2021Article
- The Osmotin-Like Protein GeneInternational journal of molecular sciences · 2020Article
- Evolution and Functional Divergence of theFrontiers in plant science · 2020Article
- Genetic architecture underlying the lignin biosynthesis pathway involves noncoding RNAs and transcription factors for growth and wood properties in Populus.Plant biotechnology journal · 2019Article
- Genomic Diversity Evaluation ofFrontiers in genetics · 2019Article
- Xylan in the Middle: Understanding Xylan Biosynthesis and Its Metabolic Dependencies Toward Improving Wood Fiber for Industrial Processing.Frontiers in plant science · 2019Review
- Accuracy of Genomic Prediction for Foliar Terpene Traits inG3 (Bethesda, Md.) · 2018Article
- Thirteen years under arid conditions: exploring marker-trait associations inBreeding science · 2018Article
- Article
- Quantitative Genetics and Genomics Converge to Accelerate Forest Tree Breeding.Frontiers in plant science · 2018Review
- Association Genetics inFrontiers in plant science · 2018Article
- Identification and allelic dissection uncover roles of lncRNAs in secondary growth of Populus tomentosa.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Allelic variation in PtoPsbW associated with photosynthesis, growth, and wood properties in Populus tomentosa.Molecular genetics and genomics : MGG · 2017Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Linkage disequilibrium (LD) mapping using natural populations results in higher resolution of marker-trait associations compared to family-based quantitative trait locus (QTL) studies. Depending on the extent of LD, it is possible to identify alleles within candidate genes associated with a trait. Analysis of a natural mutant in Arabidopsis has shown that mutations in cinnamoyl CoA reductase (CCR), a key lignin gene, affect physical properties of the secondary cell wall such as stiffness and strength. Using this gene, we tested whether LD mapping could identify alleles associated with microfibril angle (MFA), a wood quality trait affecting stiffness and strength of wood. We identified 25 common single-nucleotide polymorphism (SNP) markers in the CCR gene in Eucalyptus nitens. Using single-marker and haplotype analyses in 290 trees from a E. nitens natural population, two haplotypes significantly associated with MFA were found. These results were confirmed in two full-sib families of E. nitens and Eucalyptus globulus. In an effort to understand the functional significance of the SNP markers, we sequenced the cDNA clones and identified an alternatively spliced variant from the significant haplotype region. This study demonstrates that LD mapping can be used to identify alleles associated with wood quality traits in natural populations of trees.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.