Evidence map›Paper›PMID 16084431›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Flattening of the interventricular septum (D-shaped left ventricle) in addition to high right ventricular tracer uptake and increased right ventricular volume found on gated SPECT studies strongly correlates with right ventricular overload.

Mohammad Reza Movahed, Absalom Hepner, Paul Lizotte, Norah Milne

Open access · greenAbstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Nuclear cardiology for a cardiothoracic surgeon.Indian journal of thoracic and cardiovascular surgery · 2022
    Review
  4. Perfusion artifacts caused by marked RV enlargement.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  5. Pharmacologic stress myocardial perfusion imaging in patients with pulmonary hypertension: What do we know, and what remains to be learned?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  6. Article
  7. Ventricular asynchrony: A shift to the right?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  8. The role of nuclear imaging in pulmonary hypertension.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  9. Review
  10. Main pulmonary artery diameter from attenuation correction CT scans in cardiac SPECT accurately predicts pulmonary hypertension.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Right and left ventricular uptake with Rb-82 PET myocardial perfusion imaging: markers of left main or 3 vessel disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
    Article
  17. On the bright right side.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohammad Reza MovahedDepartment of Medicine, Division of Cardiology, University of California-Irvine Medical Center, 101 The City Drive, Orange, CA 92868-4048, USA. mmovahed@uci.edu
Absalom Hepner
Paul Lizotte
Norah Milne
University of California, Irvine Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFlattening of the interventricular septum (D-shaped left ventricle) detected during echocardiographic examination is correlated with significant right ventricular (RV) overload. There are no reports of this finding with cardiac gated single photon emission computed tomography (SPECT) imaging. We report an observational study correlating this finding with the presence of RV overload. METHODS AND

resultsRetrospectively, we compared 8 cases with flattening of the interventricular septum on cardiac gated SPECT imaging for which echocardiographic correlations and clinical data were available regarding the presence of RV overload. All patients but 1 had pulmonary hypertension ranging from 42 to 52 mm Hg measured by echocardiographic Doppler studies. All patients but 1 had reasons for RV overload (chronic obstructive pulmonary disease in 3, history of atrial septal defect in 3, pulmonary embolism in 1, and obstructive sleep apnea in 1). Septal flattening present on gated SPECT images was seen in 50% of the cases by echocardiography. Other signs of RV overload (RV enlargement, RV hypertrophy) were observed by echocardiography in 5 patients and by the gated SPECT in 7 patients.

conclusionThe presence of interventricular septal flattening on gated SPECT studies correlates with RV overload and should be routinely assessed during interpretation of gated SPECT studies.

Indexed as

AdultAgedAged, 80 and overFemaleGated Blood-Pool ImagingHeart SeptumHeart VentriclesHumansMaleMiddle AgedOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalsReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalstechnetium tc-99m tetrofosmin

Identifiers

PMID16084431
OpenAlexW2013187056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.