Evidence map›Paper›PMID 16081922›Full record

ArticleJournal of clinical microbiology2005

Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida.

Tom G Schwan, Sandra J Raffel, Merry E Schrumpf, Paul F Policastro, Julie A Rawlings, Robert S Lane, Edward B Breitschwerdt, Stephen F Porcella

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Article
  3. The ability of relapsing feverCurrent research in parasitology & vector-borne diseases · 2026
    Article
  4. Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2024
    Article
  5. Article
  6. Isolation and molecular characterization of a novel relapsing fever groupCurrent research in parasitology & vector-borne diseases · 2024
    Article
  7. Article
  8. Article
  9. A Novel Relapsing Fever GroupMicroorganisms · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. A Novel Genospecies ofMicroorganisms · 2022
    Article
  14. Article
  15. Transovarial Transmission ofMicroorganisms · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Tom G SchwanLaboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th St., Hamilton, MT 59840, USA. tom_schwan@nih.gov
Sandra J Raffel
Merry E Schrumpf
Paul F Policastro
Julie A Rawlings
Robert S Lane
Edward B Breitschwerdt
Stephen F Porcella
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USNorth Carolina State University · USTexas Department of State Health Services · USUniversity of California, Berkeley · US

Funding

LYME DISEASE IN WESTERN USA: ECOLOGY AND EPIDEMIOLOGYR01AI022501 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANE, ROBERT SIDNEY · 1985 to 2008
$3.0M
MOLECULAR BASIS FOR INFECTION BY BORRELIA BURGDORFERIZ01AI000492 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI SCHWAN, TOM · 1987 to 2008
$1.5M
NIAID NIH HHS AI22501NIAID NIH HHS R01 AI022501
6 · The paper itself

Abstract

Isolates of Borrelia turicatae, Borrelia parkeri, and the Florida canine borrelia (FCB) were examined to further phylogenetically characterize the identities of these spirochetes in the United States. DNA sequences of four chromosomal loci (the 16S rRNA gene, flaB, gyrB, and glpQ) were determined for eight isolates of B. turicatae and six isolates of B. parkeri, which grouped the spirochetes into two distinct but closely related taxa (>98% sequence identity) separate from Borrelia hermsii. The FCB was clearly separated with the group identified as B. turicatae, confirming this bacterium as a relapsing fever spirochete. Therefore, the potential for tick-borne relapsing fever in humans and other animals exists in Florida and future efforts are needed to determine the enzootic hosts and distribution of this spirochete in the southeastern United States. Analysis of plasmids demonstrated both linear and circular forms in B. turicatae but only linear plasmids in B. parkeri, which should be of interest to investigators concerned with plasmid diversity and evolution within this group of spirochetes.

Indexed as

Bacterial ProteinsBorreliaHumansPhylogenyPlasmidsRelapsing FeverSequence Analysis, DNABacterial Proteins

Identifiers

PMID16081922
PMCPMC1233929
OpenAlexW2155465240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.