ReviewCardiovascular ultrasound2005
The non-invasive documentation of coronary microcirculation impairment: role of transthoracic echocardiography.
Review in Cardiovascular ultrasound, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 87 citations in OpenAlex.
- Insulin resistance and exercise tolerance in heart failure patients: linkage to coronary flow reserve and peripheral vascular function.Cardiovascular diabetology · 2012Trial
- Non Invasive Detection of Coronary Sinus Flow Changes Over Time After CABG.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2022Article
- Coronary microcirculation and left ventricular diastolic function: comparison between patients on hemodialysis and peritoneal dialysis.Journal of echocardiography · 2021Article
- Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes.Diabetes & metabolism journal · 2021Review
- Myocardial strain indices and coronary flow reserve are only mildly affected in healthy hypertensive patients.The international journal of cardiovascular imaging · 2021Article
- Effect of Hyperglycemia on Myocardial Perfusion in Diabetic Porcine Models and Humans.Journal of Korean medical science · 2019Article
- Reduced global myocardial perfusion reserve in DCM and HCM patients assessed by CMR-based velocity-encoded coronary sinus flow measurements and first-pass perfusion imaging.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Article
- Positive effects of aggressive vasodilator treatment of well-treated essential hypertensive patients.Journal of human hypertension · 2016Article
- Hyperglycemia Induced by Glucokinase Deficiency Accelerates Atherosclerosis Development and Impairs Lesion Regression in Combined Heterozygous Glucokinase and the Apolipoprotein E-Knockout Mice.Journal of diabetes research · 2016Article
- Prognostic value of calcium score and coronary flow velocity reserve in asymptomatic diabetic patients.Cardiovascular ultrasound · 2015Article
- Article
- The relationship between retinal microvascular abnormalities and coronary heart disease: a review.The American journal of medicine · 2010Review
- Incremental value of arterial wave reflections in the determination of left ventricular diastolic dysfunction in untreated patients with essential hypertension.Journal of human hypertension · 2008Article
- Beta-blockers and coronary flow reserve: the importance of a vasodilatory action.Drugs · 2008 · on this mapReview
- Impaired coronary flow velocity reserve and aortic distensibility in patients with untreated hypercholesterolemia--an echocardiographic study.The international journal of cardiovascular imaging · 2007Article
- Factors affecting left ventricular remodeling after valve replacement for aortic stenosis. An overview.Cardiovascular ultrasound · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transthoracic Doppler echocardiographic-derived coronary flow reserve is an useful hemodynamic index to assess dysfunction of coronary microcirculation. Isolated coronary microvascular abnormalities are overt by reduced coronary flow reserve despite normal epicardial coronary arteries. These abnormalities may occur in several diseases (arterial hypertension, diabetes mellitus, hypercholesterolemia, syndrome X, aortic valve disease, hypertrophic cardiomyopathy and idiopathic dilated cardiomyopathy). The prognostic role of impaired microvascular coronary flow reserve has been shown unfavourable especially in hypertrophic or idiopathic dilated cardiomyopathies. Coronary flow reserve reduction may be reversible, for instance after regression of left ventricular hypertrophy subsequent to valve replacement in patients with aortic stenosis, after anti-hypertensive treatment or using cholesterol lowering drugs. Coronary flow reserve may increase by 30% or more after pharmacological therapy and achieve normal level >3.0. In contrast to other non invasive tools as positron emission tomography, very expensive and associated with radiation exposure, transthoracic Doppler-derived coronary flow reserve is equally non invasive but cheaper, very accessible and prone to a reliable exploration of coronary microvascular territories, otherwise not detectable by invasive coronary angiography, able to visualize only large epicardial arteries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.