ArticleEuropean journal of epidemiology2005
Early childhood risk factors associated with type 1 diabetes--is gender important?
Article in European journal of epidemiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Parental smoking, type 1 diabetes, and islet autoantibody positivity in the offspring: A systematic review and meta-analysis.Diabetic medicine : a journal of the British Diabetic Association · 2022Pooled it
- Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data.Diabetologia · 2010Pooled it
- Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies.Diabetologia · 2008Pooled it
- Type 1 Diabetes Incidence Trends in a Cohort of Turkish Children and Youth.Turkish archives of pediatrics · 2023Article
- National and sub-national burden and trend of type 1 diabetes in 31 provinces of Iran, 1990-2019.Scientific reports · 2023Article
- Maternal smoking during pregnancy and type 1 diabetes in the offspring: a nationwide register-based study with family-based designs.BMC medicine · 2022Article
- The Childhood Vaccination Schedule and the Lack of Association With Type 1 Diabetes.Pediatrics · 2021Article
- Size for gestational age affects the risk for type 1 diabetes in children and adolescents: a Swedish national case-control study.Diabetologia · 2021Article
- Effect of maternal smoking during pregnancy on childhood type 1 diabetes: a whole-of-population study.Diabetologia · 2020Article
- Association Between Rotavirus Vaccination and Type 1 Diabetes in Children.JAMA pediatrics · 2020Article
- Incidence of Type 1 Diabetes in Children Aged Below 18 Years during 2013-2015 in Northwest TurkeyJournal of clinical research in pediatric endocrinology · 2018Article
- Parental Smoking and Risk of Childhood-onset Type 1 Diabetes.Epidemiology (Cambridge, Mass.) · 2018Article
- Environmental Factors Associated with Type 1 Diabetes Development: A Case Control Study in Egypt.International journal of environmental research and public health · 2017Article
- The impact of prenatal parental tobacco smoking on risk of diabetes mellitus in middle-aged women.Journal of developmental origins of health and disease · 2015Article
- Maternal smoking during pregnancy and offspring type 1 diabetes mellitus risk: accounting for HLA haplotype.European journal of epidemiology · 2015Article
- The effect of childhood cow's milk intake and HLA-DR genotype on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young.Pediatric diabetes · 2015Article
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- Maternal smoking during pregnancy and daughters' risk of gestational diabetes and obesity.Diabetologia · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of childhood diabetes is increasing in Denmark as in the rest of the world. The aim of this investigation was to study intrauterine and early childhood risk factors for insulin dependent diabetes mellitus, and to evaluate gender differences in the effect of these. METHODS/MATERIAL: A number of 602 diabetic cases aged 0-14 years diagnosed 1996-1999 were identified from the Danish register of childhood diabetes. A total of 1490 non-diabetic healthy children matched by gender and date of birth were randomly selected from the Danish population register. In addition a combination of national register data and questionnaire data was used.
resultsHigh parental age, neonatal infections and pre-eclampsia were associated with type 1 diabetes in boys, whereas being preterm was associated with an increased risk in girls. An increased risk was associated with a family history of diabetes and amniocentesis, while a decreased risk was associated with increasing birth order and maternal smoking. In a multiple logistic regression analysis, the following risk factors were significantly associated with case-control status: maternal smoking (OR: 0.6(0.4-0.9)), neonatal infection in boys (OR: 5.5(1.4-21.8)), neonatal infection in girls (OR: 0.6(0.1-3.0)), amniocentesis (OR: 1.6(1.0-2.6)), preschool siblings (OR: 0.8(0.6-1.0)), introduction of cow's milk after the age of 3 months (OR: 0.7(0.4-0.9)) and a 1st degree family member with diabetes (OR: 9.1(95% CI:5.2-16)).
conclusionThe study showed associations between several risk factors and childhood diabetes, for some risk factors the odds ratio in boys were different from the odds ratio in girls.
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