ArticleEnvironmental health perspectives2005
Characterizing exposures to nonpersistent pesticides during pregnancy and early childhood in the National Children's Study: a review of monitoring and measurement methodologies.
Article in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurodevelopmental effects in children associated with exposure to organophosphate pesticides: a systematic review.Neurotoxicology · 2013Pooled it
- Sex-specific neurobehavioral and biochemical effects of developmental exposure to Malathion in offspring mice.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- The effect of non-organophosphate household pesticides exposure during pregnancy on infants birth sizes and growth rate: a cohort study.BMC pregnancy and childbirth · 2020Article
- Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program.Journal of exposure science & environmental epidemiology · 2020Review
- An educational intervention on the risk perception of pesticides exposure and organophosphate metabolites urinary concentrations in rural school children in Maule Region, Chile.Environmental research · 2019Article
- Self-reported residential pesticide use and survival after breast cancer.International journal of hygiene and environmental health · 2019Article
- A Pilot Study Evaluating Organochlorine and Organophosphate Pesticide Exposure in Children and Adolescents of Mexican Descent Residing in Hidalgo County, Texas.Journal of immigrant and minority health · 2019Article
- Sex-Specific Neurotoxic Effects of Organophosphate Pesticides Across the Life Course.Current environmental health reports · 2017Review
- Exposure to organophosphate (OP) pesticides and health conditions in agricultural and non-agricultural workers from Maule, Chile.International journal of environmental health research · 2017Article
- A single method for detecting 11 organophosphate pesticides in human plasma and breastmilk using GC-FPD.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2016Article
- Semivolatile organic compounds in homes: strategies for efficient and systematic exposure measurement based on empirical and theoretical factors.Environmental science & technology · 2015Article
- Identifying important life stages for monitoring and assessing risks from exposures to environmental contaminants: results of a World Health Organization review.Regulatory toxicology and pharmacology : RTP · 2014Review
- Challenges and future directions to evaluating the association between prenatal exposure to endocrine disrupting chemicals and childhood obesity.Current epidemiology reports · 2014Article
- Urinary 3,5,6-trichloro-2-pyridinol (TCPY) in pregnant women from Mexico City: distribution, temporal variability, and relationship with child attention and hyperactivity.International journal of hygiene and environmental health · 2014Article
- Characterization of residential pesticide use and chemical formulations through self-report and household inventory: the Northern California Childhood Leukemia study.Environmental health perspectives · 2013Article
- Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community.Environmental research · 2012Article
- Association between urinary 3, 5, 6-trichloro-2-pyridinol, a metabolite of chlorpyrifos and chlorpyrifos-methyl, and serum T4 and TSH in NHANES 1999-2002.The Science of the total environment · 2012Article
- Analysis of House Dust and Children's Hair for Pesticides: A Comparison of Markers of Ongoing Pesticide Exposure in Children.Journal of bioanalysis & biomedicine · 2011Article
- Where's the dust? Characterizing locations of azinphos-methyl residues in house and vehicle dust among farmworkers with young children.Journal of occupational and environmental hygiene · 2010Article
- Improving cost-effectiveness of epidemiological studies via designed missingness strategies.Statistics in medicine · 2010Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The National Children's Study is a proposed longitudinal cohort study to evaluate the relationships between children's health and the environment. Enrollment is estimated to begin in September 2005, and 100,000 children will be followed from preconception or early pregnancy until adulthood. Among multiple health outcomes, the study is proposing to investigate whether pre- and/or postnatal exposures to nonpersistent pesticides increase the risk of poor performance on neurobehavioral and cognitive exams during infancy and early childhood. Characterization of exposures will be challenging. Nonpersistent pesticides include many chemicals with biologic half-lives on the order of hours or days. Exposures can occur through multiple pathways (e.g., food and residential or agriculture pesticide use) and by multiple routes (inhalation, ingestion, dermal). Effects may depend on the developmental stage when exposure occurs. Sequential sampling is likely to be required and may involve a combination of environmental and biologic monitoring as well as collection of questionnaire data. In this article we review measurements that can be used to characterize exposures. These include biologic markers, personal and indoor air sampling techniques, collection of dust, surface and dermal wipe samples, and dietary assessment tools. Criteria for sample selection will necessitate evaluation of the time frame of exposure captured by the measurement in relationship to critical windows of susceptibility, the cost and validity of the measurements, participant burden, and variability in exposure routes across populations and at different age periods.
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