ArticleEnvironmental health perspectives2005
Mapping and prediction of coal workers' pneumoconiosis with bioavailable iron content in the bituminous coals.
Article in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Incidence and influencing factors of occupational pneumoconiosis: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Toxicity of respirable coal dust: An overview of origin, chemistry, mechanisms, and possible remedies.International journal of coal science & technology · 2026Review
- Potential Health Impacts, Treatments, and Countermeasures of Martian Dust on Future Human Space Exploration.GeoHealth · 2025Review
- In vitro toxicity assessment of bioavailable iron in coal varieties of Central India.PloS one · 2024Article
- The impact of coal mine dust characteristics on pathways to respiratory harm: investigating the pneumoconiotic potency of coals.Environmental geochemistry and health · 2023Review
- Effects of chemical composition on the lung cell response to coal particles: Implications for coal workers' pneumoconiosis.Respirology (Carlton, Vic.) · 2022Article
- Associations of SMAD4 rs10502913 and NLRP3 rs1539019 Polymorphisms with Risk of Coal Workers' Pneumoconiosis Susceptibility in Chinese Han Population.Pharmacogenomics and personalized medicine · 2022Article
- No association between pyrite content and lung cell responses to coal particles.Scientific reports · 2021Article
- Cross-section analysis of coal workers' pneumoconiosis and higher brachial-ankle pulse wave velocity within Kailuan study.BMC public health · 2017Article
- A systematic review of occupational exposure to coal dust and the risk of interstitial lung diseases.European clinical respiratory journal · 2017Review
- A Scourge Returns: Black Lung in Appalachia.Environmental health perspectives · 2016Article
- Inflammatory stress response in A549 cells as a result of exposure to coal: evidence for the role of pyrite in coal workers' pneumoconiosis pathogenesis.Chemosphere · 2013Article
- Pyrite-driven reactive oxygen species formation in simulated lung fluid: implications for coal workers' pneumoconiosis.Environmental geochemistry and health · 2012Article
- Adenine oxidation by pyrite-generated hydroxyl radicals.Geochemical transactions · 2010Article
- Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.BMC medical genomics · 2009Article
- Role of pyrite in formation of hydroxyl radicals in coal: possible implications for human health.Particle and fibre toxicology · 2006Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Based on the first National Study of Coal Workers' Pneumoconiosis (CWP) and the U.S. Geological Survey database of coal quality, we show that the prevalence of CWP in seven coal mine regions correlates with levels of bioavailable iron (BAI) in the coals from that particular region (correlation coefficient r = 0.94, p < 0.0015). CWP prevalence is also correlated with contents of pyritic sulfur (r = 0.91, p < 0.0048) or total iron (r = 0.85, p < 0.016) but not with coal rank (r = 0.59, p < 0.16) or silica (r = 0.28, p < 0.54). BAI was calculated using our model, taking into account chemical interactions of pyrite, sulfuric acid, calcite, and total iron. That is, iron present in coals can become bioavailable by pyrite oxidation, which produces ferrous sulfate and sulfuric acid. Calcite is the major component in coals that neutralizes the available acid and inhibits iron's bioavailability. Therefore, levels of BAI in the coals are determined by the available amounts of acid after neutralization of calcite and the amount of total iron in the coals. Using the linear fit of CWP prevalence and the calculated BAI in the seven coal mine regions, we have derived and mapped the pneumoconiotic potencies of 7,000 coal samples. Our studies indicate that levels of BAI in the coals may be used to predict coal's toxicity, even before large-scale mining.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.