ArticleJournal of neuro-oncology2005
Gliosarcomas: analysis of 11 cases do two subtypes exist?
Article in Journal of neuro-oncology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Article
- Article
- Multidisciplinary approaches to gliosarcoma: A case report and review of the literature.Clinical case reports · 2022Article
- Do gliosarcomas have distinct imaging features on routine MRI?The neuroradiology journal · 2021Article
- Genomic landscape of gliosarcoma: distinguishing features and targetable alterations.Scientific reports · 2021Article
- Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.BMC neurology · 2020Article
- Prognostic factors among single primary gliosarcoma cases: A study using Surveillance, Epidemiology, and End Results data from 1973-2013.Cancer medicine · 2019Article
- Clinical characteristics and disease-specific prognostic nomogram for primary gliosarcoma: a SEER population-based analysis.Scientific reports · 2019Article
- Gliosarcoma in a Young Filipino Woman: A Case Report and Review of the Literature.The American journal of case reports · 2019Review
- Clinical Characteristics of Gliosarcoma and Outcomes From Standardized Treatment Relative to Conventional Glioblastoma.Frontiers in oncology · 2019Article
- Detailed magnetic resonance imaging features of a case series of primary gliosarcoma.The neuroradiology journal · 2017Observational
- Gliosarcoma in Young Adults: A Rare Variant of Glioblastoma.World journal of oncology · 2017Article
- Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series.Journal of neuro-oncology · 2016Article
- Clinical outcome of gliosarcoma compared with glioblastoma multiforme: a clinical study in Chinese patients.Journal of neuro-oncology · 2016Article
- Pediatric gliosarcoma treated with adjuvant radiotherapy and temozolomide.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Therapeutic management of gliosarcoma in the temozolomide era.CNS oncology · 2015Review
- Primary gliosarcoma with long-survival: report of two cases and review of literature.International journal of clinical and experimental pathology · 2014Review
- Mixed granular cell astrocytoma and fibrosarcoma of the brain: a case report.International journal of clinical and experimental pathology · 2014Article
- Malignant pediatric gliosarcoma defies general survival data.Case reports in medicine · 2014Article
- Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice.Journal of neuro-oncology · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are conflicting reports regarding gliosarcomas. The goal of this study is to examine clinical, radiological, surgical and therapeutic aspects of 11 patients with gliosarcoma. Between 1993 and 2001, 11 patients with cerebral gliosarcoma were treated at our Institute. Ten patients underwent surgery and one patient had stereotactic biopsy. Four patients received whole brain radiotherapy with (60)Co, five underwent radiotherapy with LINAC extended 2 cm beyond the edema margins. One patient refused any additional treatment after surgery and one patient was not treated postoperatively for poor clinical conditions (KPS 40). Chemotherapy (temozolomide) was administered to four patients. Four patients had a prevalence of sarcomatous component that corresponded to surgical and radiological aspects similar to meningioma while six patients showed a prevalence of gliomatous component and radiological and surgical aspects similar to those of glioblastomas. Surgical resection was total in six and subtotal in four patients. Patients with prevalent sarcomatous component showed median survival time more prolonged than patients with prevalent gliomatous component (71 +/- 6 weeks vs. 63 +/- 6; P=0.0417). Moreover, the survival rate differed in relation to the therapy: patients treated with multimodality therapy (surgery, radiotherapy and chemotherapy) had a longer survival time than patients treated in single or bimodality. Despite prognosis of gliosarcomas remains poor, a multidisciplinary approach (surgery, radiotherapy and chemotherapy) seems to be associated with slight more prolonged survival times.
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Registered trials
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