Evidence map›Paper›PMID 16078087›Full record

ReviewEuropean archives of psychiatry and clinical neuroscience2006

Do recent efficacy data on the drug treatment of acute bipolar depression support the position that drugs other than antidepressants are the treatment of choice? A conceptual review.

Hans-Jürgen Möller, Heinz Grunze, Karl Broich

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in European archives of psychiatry and clinical neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. State of the art: treatment of bipolar disorders.CNS neuroscience & therapeutics · 2012
    Review
  7. Article
  8. Article
  9. Management of bipolar depression.Indian journal of psychological medicine · 2011
    Article
  10. Evidence-based medicine in psychopharmacotherapy: possibilities, problems and limitations.European archives of psychiatry and clinical neuroscience · 2010
    Article
  11. Is evidence sufficient for evidence-based medicine?European archives of psychiatry and clinical neuroscience · 2009
    Review
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hans-Jürgen MöllerDepartment of Psychiatry, Ludwig-Maximilians-University, Nussbaumstrasse 7, 80336 Munich, Germany. hans-juergen.moeller@med.uni-muenchen.de
Heinz Grunze
Karl Broich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This conceptual review summarises the results of relevant studies on antidepressants, mood stabilisers such as lithium and anticonvulsants, and second generation antipsychotics in the indication of bipolar depression. Based on methodological and clinical considerations, the position of antidepressants and the possible alternatives in this indication are reviewed very carefully. In addition the regulatory requirements for licensing a drug for the indication "short-term treatment of bipolar depression" are described.

Indexed as

Acute DiseaseAffectAnticonvulsantsAntidepressive AgentsAntimanic AgentsAntipsychotic AgentsBipolar DisorderDrug ApprovalDrug Therapy, CombinationHumansLithium CarbonateRandomized Controlled Trials as TopicTreatment OutcomeAnticonvulsantsAntidepressive AgentsAntimanic AgentsAntipsychotic AgentsLithium Carbonate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.