ReviewEpilepsy & behavior : E&B2005
Systemic prenatal insults disrupt telencephalon development: implications for potential interventions.
Review in Epilepsy & behavior : E&B, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- hUC-MSC extracellular vesicles protect against hypoxic-ischemic brain injury by promoting NLRP3 ubiquitination.Biomolecules & biomedicine · 2025Article
- Correspondence on "Recognition and Management of Delirium in the Neonatal Intensive Care Unit: Case Series From a Single-Center Level IV Intensive Care Unit".Journal of child neurology · 2024Article
- Prenatal and postnatal insults differentially contribute to executive function and cognition: Utilizing touchscreen technology for perinatal brain injury research.Experimental neurology · 2022Article
- SARS-CoV-2 (COVID-19) as a possible risk factor for neurodevelopmental disorders.Frontiers in neuroscience · 2022Review
- Animal models of developmental motor disorders: parallels to human motor dysfunction in cerebral palsy.Journal of neurophysiology · 2019Article
- Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood.Frontiers in physiology · 2019Article
- Neonatal erythropoietin mitigates impaired gait, social interaction and diffusion tensor imaging abnormalities in a rat model of prenatal brain injury.Experimental neurology · 2018Article
- Erythropoietin Modulates Cerebral and Serum Degradation Products from Excess Calpain Activation following Prenatal Hypoxia-Ischemia.Developmental neuroscience · 2016Article
- Delayed effect of prenatal exposure to hypoxia on the susceptibility of rats to electric seizures.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2015Article
- Postnatal Erythropoietin Mitigates Impaired Cerebral Cortical Development Following Subplate Loss from Prenatal Hypoxia-Ischemia.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Protein kinase C-dependent growth-associated protein 43 phosphorylation regulates gephyrin aggregation at developing GABAergic synapses.Molecular and cellular biology · 2015Article
- Preclinical Models of Encephalopathy of Prematurity.Developmental neuroscience · 2015Review
- Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone.Frontiers in cellular neuroscience · 2015Article
- Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury.Molecular and cellular neurosciences · 2014Article
- Effect of transient maternal hypotension on apoptotic cell death in foetal rat brain.Balkan medical journal · 2014Article
- Developmental dynamics of radial vulnerability in the cerebral compartments in preterm infants and neonates.Frontiers in neurology · 2014Article
- Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia.Annals of neurology · 2012Article
- Neuroanatomical, sensorimotor and cognitive deficits in adult rats with white matter injury following prenatal ischemia.Brain pathology (Zurich, Switzerland) · 2012Article
- Structural covariance in the cortex of very preterm adolescents: a voxel-based morphometry study.Human brain mapping · 2011Article
- Postnatal erythropoietin treatment mitigates neural cell loss after systemic prenatal hypoxic-ischemic injury.Journal of neurosurgery. Pediatrics · 2010Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Infants born prematurely are prone to chronic neurologic deficits including cerebral palsy, epilepsy, cognitive delay, behavioral problems, and neurosensory impairments. In affected children, imaging and neuropathological findings demonstrate significant damage to white matter. The extent of cortical damage has been less obvious. Advances in the understanding of telencephalon development provide insights into how systemic intrauterine insults affect the developing white matter, subplate, and cortex, and lead to multiple neurologic impairments. In addition to white matter oligodendrocytes and axons, other elements at risk for perinatal brain injury include subplate neurons, GABAergic neurons migrating through white matter and subplate, and afferents of maturing neurotransmitter systems. Common insults including hypoxia-ischemia and infection often affect the developing brain differently than the mature brain, and insults precipitate a cascade of damage to multiple neural lineages. Insights from development can identify potential targets for therapies to repair the damaged neonatal brain before it has matured.
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Registered trials
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