SynthesisThorax2005
Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysis.
Synthesis in Thorax, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02852499 (SEPAGES), which is not on this map. Cited by 73 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SEPAGES : Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
Who cites it
73 citing papers in PubMed, 4 syntheses or guidelines pooled it, 208 citations in OpenAlex.
- Assessment of comorbidities and prognosis in patients with COPD diagnosed with the fixed ratio and the lower limit of normal: a systematic review and meta-analysis.Respiratory research · 2020Pooled it
- Chained Risk Assessment for Life-Long Disease Burden of Early Exposures - Demonstration of Concept Using Prenatal Maternal Smoking.International journal of environmental research and public health · 2020Pooled it
- Preterm birth, infant weight gain, and childhood asthma risk: a meta-analysis of 147,000 European children.The Journal of allergy and clinical immunology · 2014Pooled it
- Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index.International journal of epidemiology · 2011Pooled it
- Effects of antenatal multiple micronutrient supplementation on lung function in mid-childhood: follow-up of a double-blind randomised controlled trial in Nepal.The European respiratory journal · 2015Trial
- Bibliometric analysis of reviews of outcomes for adults with a complex perinatal history.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Association of birth weight with lung function and the mediating role of gut microbiota: A STROBE 2-step Mendelian randomization study.Medicine · 2025Article
- Association between birth weight and chronic obstructive pulmonary disease in the UK Biobank: a prospective cohort study.BMJ open respiratory research · 2024Article
- Macrophage Polarization and Functions in Pathogenesis of Chronic Obstructive Pulmonary Disease.International journal of molecular sciences · 2024Review
- Gold 2023: Highlights for primary care.NPJ primary care respiratory medicine · 2023Article
- Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary.The European respiratory journal · 2023Article
- Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary.American journal of respiratory and critical care medicine · 2023Article
- Small for gestational age is associated with reduced lung function in middle age: A prospective study from first to fifth decade of life.Respirology (Carlton, Vic.) · 2023Article
- Early Origins of Chronic Obstructive Pulmonary Disease: Prenatal and Early Life Risk Factors.International journal of environmental research and public health · 2023Review
- Can birth weight predict offspring's lung function in adult age? Evidence from two Swedish birth cohorts.Respiratory research · 2022Article
- The Association of Self-Reported Birthweight with Lung Function and Respiratory Diseases: Results from a Multi-Centre, Multi-Case Control Study in Italy.International journal of environmental research and public health · 2022Article
- Lifelong Lung Sequelae of Prematurity.International journal of environmental research and public health · 2022Review
- Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.American journal of respiratory and critical care medicine · 2022Observational
- Influence of maternal vomiting during early pregnancy on school-age respiratory health.Pediatric pulmonology · 2022Article
- Non-linear association of birth weight with lung function and risk of asthma: A population-based study.Frontiers in public health · 2022Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to examine the associations between birth weight and lung function in a cohort of women aged 60-79 years and to combine these results with those from other published studies in a systematic review and meta-analysis.
methodsThe associations of self-reported birth weight with adult lung function (forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and forced expiratory flow rate during mid expiration (FEF(25-75)), all measured using standard procedures, were assessed in a cross sectional study of 2257 British women aged 60-79 years. A detailed literature search was used to identify all published studies of the association, and meta-analysis was used to pool the results from our study and all published studies.
resultsThere were positive linear associations between birth weight and all three measures of lung function in simple age and examining nurse adjusted regression models. However, with adjustment for height (squared), all three associations attenuated towards the null: adjusted (age, nurse, height2) change in FEV1 per 1 kg birth weight was 0.01 l (95% CI -0.02 to 0.04); in FVC was 0.02 l (95% CI -0.02 to 0.07), and in FEF(25-75) was 0.00 l (95% CI -0.04 to 0.04). Further adjustment for life course socioeconomic position, adult body mass index, and smoking did not alter these associations. The results were similar among life long non-smokers and those who had ever smoked. A meta-analysis of eight studies of adults suggested that there was a positive association between birth weight and FEV1: pooled increase in FEV1 per 1 kg in birth weight 0.048 l (95% CI 0.026 to 0.070) adjusted for age, smoking, and height (or height squared). There was no evidence of small study bias in this meta-analysis.
conclusionsThere is a modest positive association between birth weight and lung function which indicates that intrauterine factors might have a role in lung development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.