ArticleJournal of the American Society for Mass Spectrometry2005
Ganglioside analysis by thin-layer chromatography matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometry.
Article in Journal of the American Society for Mass Spectrometry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 81 citations in OpenAlex.
- Manipulation of Ion Types via Gas-Phase Ion/Ion Chemistry for the Structural Characterization of the Glycan Moiety on Gangliosides.Analytical chemistry · 2021Article
- Detection of Multiple Sclerosis Biomarkers in Serum by Ganglioside Microarrays and Surface Plasmon Resonance Imaging.ACS sensors · 2020Article
- AP-MALDI Mass Spectrometry Imaging of Gangliosides Using 2,6-Dihydroxyacetophenone.Journal of the American Society for Mass Spectrometry · 2018Article
- Direct analysis of sialylated or sulfated glycosphingolipids and other polar and neutral lipids using TLC-MS interfaces.Journal of lipid research · 2014Article
- Localization and imaging of gangliosides in mouse brain tissue sections by laserspray ionization inlet.Journal of lipid research · 2012Article
- Structural characterization of monosialo-, disialo- and trisialo-gangliosides by negative ion AP-MALDI-QIT-TOF mass spectrometry with MS(n) switching.Neurochemical research · 2012Article
- Scientific literature addressing detection of monosialoganglioside: A 10-year bibliometric analysis.Neural regeneration research · 2012Article
- Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging.Biochimica et biophysica acta · 2011Review
- MALDI imaging of lipid biochemistry in tissues by mass spectrometry.Chemical reviews · 2011Article
- Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Chemical reviews · 2011Review
- Vacuum compatible sample positioning device for matrix assisted laser desorption∕ionization Fourier transform ion cyclotron resonance mass spectrometry imaging.The Review of scientific instruments · 2011Article
- Gangliosides' analysis by MALDI-ion mobility MS.The Analyst · 2011Article
- Localization and imaging of sialylated glycosphingolipids in brain tissue sections by MALDI mass spectrometry.Glycobiology · 2010Article
- Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers.Journal of lipid research · 2009Article
- Mass spectrometric detection of multiple extended series of neutral highly fucosylatedInternational journal of mass spectrometry · 2008Article
- High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2008Article
- Analysis of native milk oligosaccharides directly from thin-layer chromatography plates by matrix-assisted laser desorption/ionization orthogonal-time-of-flight mass spectrometry with a glycerol matrix.Journal of the American Society for Mass Spectrometry · 2006Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Metastable decomposition of ions generated in matrix-assisted laser desorption/ionization (MALDI) mass spectrometers complicates analysis of biological samples that have labile bonds. Recently, several academic laboratories and manufacturers of commercial instruments have designed instruments that introduce a cooling gas into the ion source during the MALDI event and have shown that the resulting vibrational cooling stabilizes these labile bonds. In this study, we compared stabilization and detection of desorbed gangliosides on a commercial orthogonal time-of-flight (oTOF) instrument with results we reported previously that had been obtained on a home-built Fourier transform mass spectrometer. Decoupling of the desorption/ionization from the detection steps resulted in an opportunity for desorbing thin-layer chromatography (TLC)-separated gangliosides directly from a TLC plate without compromising mass spectral accuracy and resolution of the ganglioside analysis, thus coupling TLC and oTOF mass spectrometry. The application of a declustering potential allowed control of the matrix cluster and matrix adduct formation, and, thus, enhanced the detection of the gangliosides.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.