Trial reportWorld journal of gastroenterology2005
Visceral response to acute retrograde gastric electrical stimulation in healthy human.
Trial report in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Trial
- Percutaneous electrical neurostimulation of dermatome T6 for appetite reduction and weight loss in morbidly obese patients.Obesity surgery · 2014Trial
- Methods and Techniques for Closed-Loop Gastrointestinal Pacing.Neurogastroenterology and motility · 2026Article
- Endoscopic mucosal electrodes: New directions for recording and regulating gastric myoelectric activity.Frontiers in surgery · 2022Review
- Updates on gastric electrical stimulation to treat obesity: Systematic review and future perspectives.World journal of gastrointestinal endoscopy · 2014Article
- The acute effects of a new type of implantable gastric electrical stimulators featuring varied pulse widths on beagle dogs' food intake and gastric accommodation.Obesity surgery · 2014Article
- Parameter selection and stimulating effects of an adjustable gastric electrical stimulator in dogs.Obesity surgery · 2014Article
- Gastric stimulation for weight loss.World journal of gastroenterology · 2012Review
- Multiscale modeling of gastrointestinal electrophysiology and experimental validation.Critical reviews in biomedical engineering · 2010Review
- Devices for the treatment of obesity: will understanding the physiology of satiety unravel new targets for intervention?Journal of diabetes science and technology · 2008Article
- A new laparoscopic technique for weight reduction with implanted gastric banding basket.Obesity surgery · 2008Article
- Electrical stimulation as treatment for obesity and diabetes.Journal of diabetes science and technology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the visceral response to acute retrograde gastric electrical stimulation (RGES) in healthy humans and to derive optimal parameters for treatment of patients with obesity.
methodsRGES with a series of effective parameters were performed via a bipolar mucosal electrode implanted along the great curvature 5 cm above pylorus of stomach in 12 healthy human subjects. Symptoms associated with dyspepsia and other discomfort were observed and graded during RGES at different settings, including long pulse and pulse train. Gastric myoelectrical activity at baseline and during different settings of stimulation was recorded by a multi-channel electrogastrography.
resultsThe gastric slow wave was entrained in all the subjects at the pacing parameter of 9 cpm in frequency, 500 ms in pulse width, and 5 mA in amplitude. The frequently appeared symptoms during stimulation were satiety, bloating, discomfort, pain, sting, and nausea. The total symptom score for each subject significantly increased as the amplitude or pulse width was adjusted to a higher scale in both long pulse and pulse train. There was a wide diversity of visceral responses to RGES among individuals.
conclusionAcute RGES can result in a series of symptoms associated with dyspepsia, which is beneficial to the treatment of obesity. Optimal parameter should be determined according to the individual sensitivity to electrical stimulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.