Evidence map›Paper›PMID 16048969›Full record

ArticleAntimicrobial agents and chemotherapy2005

In vitro synergistic interaction between amphotericin B and micafungin against Scedosporium spp.

Clara Yustes, Josep Guarro

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 46 citations in OpenAlex.

  1. Amphotericin B resistance inAntimicrobial agents and chemotherapy · 2026
    Article
  2. Amphotericin B Resistance inbioRxiv : the preprint server for biology · 2026
    Article
  3. DisseminatedASM case reports · 2025
    Article
  4. Article
  5. Microorganisms · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Melanized fungi in human disease.Clinical microbiology reviews · 2010
    Review
  12. Article
  13. Article
  14. Infections caused by Scedosporium spp.Clinical microbiology reviews · 2008
    Review
  15. Comparison of echinocandin antifungals.Therapeutics and clinical risk management · 2007
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Clara YustesUnitat de Microbiologia, Facultat de Medicina, Universitat Rovira i Virgili, Carrer Sant Llorenç, 21, 43201 Reus, Spain.
Josep Guarro
Universidad Rovira i Virgili · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro interaction between amphotericin B and micafungin against 36 isolates of Scedosporium spp. has been evaluated using checkerboard assays and the minimal effective concentration endpoint. Synergy was found for 82.4% of Scedosporium prolificans isolates and for 31.6% of Scedosporium apiospermum isolates. Antagonism was not observed.

Indexed as

Amphotericin BAntifungal AgentsDrug SynergismEchinocandinsHumansLipopeptidesLipoproteinsMicafunginMicrobial Sensitivity TestsPeptides, CyclicScedosporiumAmphotericin BAntifungal AgentsEchinocandinsLipopeptidesLipoproteinsMicafunginPeptides, Cyclic

Identifiers

PMID16048969
PMCPMC1196235
OpenAlexW2135775822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.