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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2005

Are indirect utility measures reliable and responsive in rheumatoid arthritis patients?

Carlo A Marra, Amir A Rashidi, Daphne Guh, Jacek A Kopec, Michal Abrahamowicz, John M Esdaile, John E Brazier, Paul R Fortin, Aslam H Anis

Abstract readValidation Study
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. How valid and responsive are generic health status measures, such as EQ-5D and SF-36, in schizophrenia? A systematic review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
    Pooled it
  2. Randomized controlled trial protocol feasibility: The Wheelchair Self-Efficacy Enhanced for Use (WheelSeeU).Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2014
    Trial
  3. Trial
  4. Evaluation of the responsiveness of Short Form-12 Health Survey version 2 (SF-12v2) in Chinese patients with hypertension in primary care.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  5. Evaluation of the internal and external responsiveness of Short Form-12 Health Survey version 2 (SF-12v2) in patients with type 2 diabetes mellitus.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
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  7. Article
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  9. The psychometric testing of the Thai version of the Health Utilities Index in patients with ischemic heart disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013
    Article
  10. Developing the Chinese version of the new 5-level EQ-5D descriptive system: the response scaling approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013
    Article
  11. Article
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  14. The comparative responsiveness of the EQ-5D and SF-6D to change in patients with inflammatory arthritis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2009
    Article
  15. Article
  16. Comparison of health-related quality of life measures for chronic renal failure: quality of well-being scale, short-form-6D, and the kidney disease quality of life instrument.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2008
    Article
  17. Prevalence and factors associated with thriving in older adulthood: a 10-year population-based study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2008
    Article
  18. Comparing preference-based quality-of-life measures: results from rehabilitation patients with musculoskeletal, cardiovascular, or psychosomatic disorders.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2008
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlo A MarraFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Amir A Rashidi
Daphne Guh
Jacek A Kopec
Michal Abrahamowicz
John M Esdaile
John E Brazier
Paul R Fortin
Aslam H Anis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreference-based, generic measures are increasingly being used to measure quality of life and as sources for quality weights in the estimation of Quality Adjusted Life Years (QALYs) in rheumatoid arthritis (RA). However, among the most commonly used instruments (the Health Utilities Index 2 and 3 [HUI2 and HUI3], the EuroQoL-5D [EQ-5D], and the Short Form-6D [SF-6D], there has been little comparative research. Therefore, we examined the reliability and responsiveness of these measures and the Rheumatoid Arthritis Quality of Life (RAQoL) and the Health Assessment Questionnaire (HAQ) in a sample of RA patients. MAJOR

findingsTest-retest reliability was acceptable for all of the instruments with the exception of the EQ-5D. Using two external criteria to define change (a patient transition question and categories of the patient global assessment of disease activity VAS), the RAQoL was the most responsive of the instruments. For the indirect utility instruments, the HUI3 and the SF-6D were the most responsive for measuring positive change. On average, for patients whose RA improved, the absolute change was highest for the HUI3.

conclusionsThe HUI3 and the SF-6D appear to be the most responsive of the preference-based instruments in RA. However, differences in the magnitude of the absolute change scores have important implications for cost-effectiveness analyses.

Indexed as

Quality-Adjusted Life YearsQuality of LifeSickness Impact ProfileSurveys and QuestionnairesArthritis, RheumatoidBritish ColumbiaHumansPain MeasurementPsychometricsRheumatology

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.