ArticleBritish journal of sports medicine2005
Response of bone metabolism related hormones to a single session of strenuous exercise in active elderly subjects.
Article in British journal of sports medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- The Bone Biomarker Response to an Acute Bout of Exercise: A Systematic Review with Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Whole Body Vibration Exposure on Markers of Bone Turnover, Body Composition, and Physical Functioning in Breast Cancer Patients Receiving Aromatase Inhibitor Therapy: A Randomized Controlled Trial.Integrative cancer therapies · 2018Trial
- Calcium supplementation and parathyroid hormone response to vigorous walking in postmenopausal women.Medicine and science in sports and exercise · 2014Trial
- The effect of 12 weeks of resistance training on hormones of bone formation in young sedentary women.European journal of applied physiology · 2013Trial
- Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis.Medicine and science in sports and exercise · 2011Trial
- Effect of impact exercise on bone metabolism.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009Trial
- Changes in the concentration of bone turnover markers in men after maximum intensity exercise.PeerJ · 2024Article
- Comparison of selected prooxidant-antioxidant balance and bone metabolism indicators and BDNF levels between older women with different levels of physical activity.BMC geriatrics · 2023Article
- Bone Turnover Markers: Basic Biology to Clinical Applications.Endocrine reviews · 2023Article
- Exercise improves subchondral bone microenvironment through regulating bone-cartilage crosstalk.Frontiers in endocrinology · 2023Review
- Effect of physical training on parathyroid hormone and bone turnover marker profile in relation to vitamin D supplementation in soccer players.Biology of sport · 2022Article
- Acute Effects of Strength and Endurance Training on Bone Turnover Markers in Young Adults and Elderly Men.Frontiers in endocrinology · 2022Article
- Environmental Factors That Affect Parathyroid Hormone and Calcitonin Levels.International journal of molecular sciences · 2021Review
- Smoking behavior and circulating vitamin D levels in adults: A meta-analysis.Food science & nutrition · 2021Review
- Effect of Application of Different Exercise Intensities on Vitamin D and Parathormone in Children with Down's Syndrome.Applied bionics and biomechanics · 2021Article
- Response of Bone Metabolism Markers to Ice Swimming in Regular Practitioners.Frontiers in physiology · 2021Article
- Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.International journal of molecular sciences · 2020Review
- Effects of natural polyphenol-rich pomegranate juice supplementation on plasma ion and lipid profiles following resistance exercise: a placebo-controlled trial.Nutrition & metabolism · 2020Article
- Effect of a 6-week supervised detraining period on bone metabolism markers and their association with ergometrics and components of the hypothalamic-pituitary-gonadal (HPG) axis in professional male soccer players.Journal of bone and mineral metabolism · 2019Article
- Loss of the PTH/PTHrP receptor along the osteoblast lineage limits the anabolic response to exercise.PloS one · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of strenuous exercise on bone metabolism and related hormones in elderly subjects.
methodsTwenty one active elderly subjects (11 men and 10 women; mean age 73.3 years) showing a mean theoretical Vo2max of 151.4% participated. Concentrations of plasma ionised calcium (iCa), serum intact parathyroid hormone (iPTH), 25-hydroxyvitamin D (25(OH)D), and 1.25-dihydroxy-vitamin D3 (1.25(OH)2D3), as well as the bone biochemical markers type I collagen C-telopeptide for bone resorption and osteocalcin and bone alkaline phosphatase for bone formation, were analysed before and after a maximal incremental exercise test.
resultsAt basal level, iPTH was positively correlated with age (r = 0.56, p < 0.01) and negatively correlated with 25(OH)D (r = -0.50; p < 0.01) and 1.25(OH)2D3 (r = -0.47; p < 0.05). Moreover, 25(OH)D and 1.25(OH)2D3 levels were negatively correlated with age (r = -0.50, p < 0.01 and r = -0.53, p < 0.01, respectively). After exercise, iCa and 25(OH)D decreased (p < 0.001 and p = 0.01, respectively) while iPTH increased (p < 0.001). The levels of 1.25(OH)2D3, bone biochemical markers, haematocrit, and haemoglobin were unchanged. The variations in iCa and 25(OH)D were not related to age and/or sex. The iPTH variation was directly related to basal iPTH levels (p < 0.01) and indirectly related to age.
conclusionsIn active elderly subjects, strenuous exercise disturbed calcium homeostasis and bone related hormones without immediate measurable effect on bone turnover. Although an increase in iPTH could have an anabolic action on bone tissue, our findings from our short term study did not allow us to conclude that such action occurred.
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Registered trials
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