ReviewPflugers Archiv : European journal of physiology2005
Protein-protein interaction and functionTRPC channels.
Review in Pflugers Archiv : European journal of physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 65 citations in OpenAlex.
- Identification of 14-3-3 Proteins as Binding Partners of TRP Channels.Journal of chemical information and modeling · 2026Article
- Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3.BMC biology · 2022Article
- Mechanisms and significance of CaCurrent opinion in physiology · 2020Article
- The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels.PloS one · 2013Article
- The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels.Frontiers in bioscience (Landmark edition) · 2012Review
- Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions.Journal of cell science · 2010Article
- C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation.The Journal of biological chemistry · 2010Article
- An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs.FEBS letters · 2010Review
- Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.The Journal of cell biology · 2008Article
- Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.Biochimica et biophysica acta · 2008Article
- Organization and function of TRPC channelosomes.Pflugers Archiv : European journal of physiology · 2007Review
- Inositol triphosphate-mediated Ca2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels.Nature cell biology · 2007Article
- Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components.The Journal of biological chemistry · 2007Article
- TRP channels: a TR(I)P through a world of multifunctional cation channels.Pflugers Archiv : European journal of physiology · 2005Review
- The dynamic complexity of the TRPC1 channelosome.Channels (Austin, Tex.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since their identification in the concluding years of the last century, the mammalian transient receptor potential (canonical) (TRPC) channels have remained in the limelight as the primary candidates for the Ca(2+) entry pathway activated by the hormones, growth factors, and neurotransmitters that exert their effect through activation of PLC. Although TRPC channels have been shown clearly to mediate, at least in part, receptor-activated Ca(2+) entry in literally all cell types, several of their central characteristics, as recorded in expression systems using recombinant channels, differ from those of the native receptor-dependent Ca(2+) influx channels. The present review attempts to highlight the interaction of TRPC channels with other proteins, which may explain the variability of TRPC channel activation and regulatory mechanisms observed with the native and recombinant channels. These include the homologous and heterotopous interactions of TRPC channel isoforms, the interaction of TRPC channels with calmodulin, PLCgamma, IP(3) receptors, and with scaffolding proteins like InaD, EBP50/NEHRF, caveolin, Janctate and Homers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.