ArticleJournal of molecular evolution2005
Codon bias and noncoding GC content correlate negatively with recombination rate on the Drosophila X chromosome.
Article in Journal of molecular evolution, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Causes and consequences of sex-chromosome turnovers in Diptera.Evolution letters · 2026Article
- Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species.Genetics · 2024Article
- Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species.bioRxiv : the preprint server for biology · 2023Article
- Meiotic, genomic and evolutionary properties of crossover distribution in Drosophila yakuba.PLoS genetics · 2022Article
- Article
- Transcription-Associated Compositional Skews in Drosophila Genes.Genome biology and evolution · 2018Article
- Emergence, Retention and Selection: A Trilogy of Origination for Functional De Novo Proteins from Ancestral LncRNAs in Primates.PLoS genetics · 2015Article
- Article
- Positive and purifying selection on the Drosophila Y chromosome.Molecular biology and evolution · 2014Article
- Genome diversity and divergence in Drosophila mauritiana: multiple signatures of faster X evolution.Genome biology and evolution · 2014Article
- Recurrent turnover of chromosome-specific satellites in Drosophila.Genome biology and evolution · 2014Article
- Evidence that natural selection on codon usage in Drosophila pseudoobscura varies across codons.G3 (Bethesda, Md.) · 2014Article
- The relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster.Molecular biology and evolution · 2014Article
- Fine-scale heterogeneity in crossover rate in the garnet-scalloped region of the Drosophila melanogaster X chromosome.Genetics · 2013Article
- Codon usage bias and effective population sizes on the X chromosome versus the autosomes in Drosophila melanogaster.Molecular biology and evolution · 2013Article
- Genomic dynamics of transposable elements in the western clawed frog (Silurana tropicalis).Genome biology and evolution · 2013Article
- Article
- Compositional bias is a major determinant of the distribution pattern and abundance of palindromes in Drosophila melanogaster.Journal of molecular evolution · 2012Article
- The many landscapes of recombination in Drosophila melanogaster.PLoS genetics · 2012Article
- Molecular evolution in nonrecombining regions of the Drosophila melanogaster genome.Genome biology and evolution · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The patterns and processes of molecular evolution may differ between the X chromosome and the autosomes in Drosophila melanogaster. This may in part be due to differences in the effective population size between the two chromosome sets and in part to the hemizygosity of the X chromosome in Drosophila males. These and other factors may lead to differences both in the gene complements of the X and the autosomes and in the properties of the genes residing on those chromosomes. Here we show that codon bias and recombination rate are correlated strongly and negatively on the X chromosome, and that this correlation cannot be explained by indirect relationships with other known determinants of codon bias. This is in dramatic contrast to the weak positive correlation found on the autosomes. We explored possible explanations for these patterns, which required a comprehensive analysis of the relationships among multiple genetic properties such as protein length and expression level. This analysis highlights conserved features of coding sequence evolution on the X and the autosomes and illuminates interesting differences between these two chromosome sets.
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Registered trials
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