Evidence map›Paper›PMID 16041054›Full record

ArticleInfection and immunity2005

Investigation of oxidative stress defenses of Neisseria gonorrhoeae by using a human polymorphonuclear leukocyte survival assay.

Kate L Seib, Mark P Simons, Hsing-Ju Wu, Alastair G McEwan, William M Nauseef, Michael A Apicella, Michael P Jennings

Abstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Neutrophil CEACAMs and the Inflammatory Response toJournal of innate immunity · 2026
    Review
  2. Article
  3. mBio · 2024
    Article
  4. bioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Gonorrhea - an evolving disease of the new millennium.Microbial cell (Graz, Austria) · 2016
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kate L SeibThe School of Molecular and Microbial Sciences, The University of Queensland, Brisbane 4072, Australia.
Mark P Simons
Hsing-Ju Wu
Alastair G McEwan
William M Nauseef
Michael A Apicella
Michael P Jennings

Funding

PYSCHOPHYSICAL, PARTNER SPECIFIC &COITUS SPECIFIC RISK &PROTECTIVE FACTORSU19AI043924 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI ORR, DONALD P · 1998 to 2003
$5.6M
THE ROLE OF CHLAMYDIA TRACHOMATIS IN ENDOMETRIAL CAUSES OF INFERTILITYU19AI038515 · NIAID · BOSTON MEDICAL CENTER · PI WETZLER, LEE MARK · 1995 to 2003
$4.3M
THE BIOLOGY OF PATHOGENIC NEISSERIAR01AI045728 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 1999 to 2010
$3.7M
Human neutrophils, phospholipase A2 and S.aureus: microbial targets and responsesI01BX000513 · VA · IOWA CITY VA MEDICAL CENTER · PI NAUSEEF, WILLIAM M. · 2009 to 2017
–
BLRD VA I01 BX000513NIAID NIH HHS AI38515NIAID NIH HHS AI43924NIAID NIH HHS AI45728NIAID NIH HHS R01 AI045728NIAID NIH HHS U19 AI038515
6 · The paper itself

Abstract

Neisseria gonorrhoeae has well-characterized oxidative stress defense systems that protect against oxidative killing in in vitro assays. In contrast, mutant strains of N. gonorrhoeae lacking oxidative stress defenses are identical to the wild type when tested in an ex vivo survival assay using human polymorphonuclear leukocytes.

Indexed as

Biological AssayCell SurvivalGonorrheaHumansMutationNeisseria gonorrhoeaeNeutrophilsOxidative Stress

Identifiers

PMID16041054
PMCPMC1201195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.